With the current COVID-19 pandemic and social distancing measures being enacted, many of us find ourselves working from home and spending most, if not all, of our time indoors.  According to the most recent report from the AVMA, nearly 57% of all US households own a pet.  So, while some may be worried about maintaining a healthy lifestyle, what about our furry friends? 

Maintaining physical exercise is not only important for ourselves but for our pets as well.  In a previous blog, we discussed the potential benefits of regular walks for your dog.  Follow local ordinances regarding social distancing and use your best judgement when it comes to exercising your dog outside during the current pandemic.  If you find that you cannot continue your usual routine, consider additional ways to keep your pet active.

Playing games such as fetch and tug-of-war may be good ways to keep your dog both physically and mentally stimulated.  Toys that require your dog to chew or uncover treats can also help with mental stimulation.  Similarly, cats may also enjoy playing with toys as a form of physical and mental stimulation.  Additionally, there are many videos online that show how to teach your dog or cat new tricks.

It may also be a wise decision to consider an emergency kit for your pets.  Your kit can include food, treats, medications, toys, blanket or bed, and anything that you might need for your pet.  Many veterinary hospitals remain open however several have modified services and/or hours.  Check with your veterinarian to determine if they are still open and what their current operating protocol is so that you can plan accordingly.    

The good news is the CDC is currently reporting that there is no evidence that companion animals can spread, or are a source of, COVID-19.  See our recent blog for more information on COVID-19 and pets.  And as a reminder to our clients and potential clients, as a critical medicines provider, VetStem remains open to process all stem cell requests.  Click here to locate a VetStem provider in your area.

Coronavirus has impacted the world, including veterinary clinics and pet owners.  With the current situation surrounding Coronavirus Disease 2019 (COVID-19), there have been questions regarding the possible transmission of the virus from humans to pets (including horses) and vice versa.

I am not an expert on COVID-19, but I am a veterinarian, an epidemiologist, and I have been studying disease spread and animal health for over 35 years.  Our VetStem team has been gathering information from trusted sources.  The following are my opinions and also referenced opinions of the Centers for Disease Control and Prevention (CDC) and the American Veterinary Medical Association (AVMA).  Use these resources to assist in guiding your actions relative to COVID-19 and your pets.

Though this continues to be a rapidly developing situation, the CDC is currently reporting that they have not received any reports of pets sick with COVID-19.  They also stated, “In the United States, there is no evidence to suggest that any animals, including pets, livestock, or wildlife, might be a source of COVID-19 infection at this time.”  The CDC recommends if you are not ill with COVID-19, you can interact with your pet as you normally would however do practice good hygiene during your interactions (wash hands before and after interacting).

CDC recommendations if you are sick with COVID-19:

• “If you are sick with COVID-19 (either suspected or confirmed), you should restrict contact with pets and other animals, just like you would around other people. Although there have not been reports of pets or other animals becoming sick with COVID-19, it is still recommended that people sick with COVID-19 limit contact with animals until more information is known about the virus. This can help ensure both you and your animals stay healthy.”
• “When possible, have another member of your household care for your animals while you are sick. Avoid contact with your pet including, petting, snuggling, being kissed or licked, and sharing food. If you must care for your pet or be around animals while you are sick, wash your hands before and after you interact with them.”

Stem Cell Treatment Availability

• We want to assure veterinarians and pet owners that VetStem’s laboratory operations are up and running and we are processing samples and shipping out cell doses to veterinarians as per our normal operations. 
• Veterinarians are critical to maintaining the health of our animals and VetStem is following the CDC guidelines to keep our dedicated staff healthy and working.  As you may know, our laboratories are maintained at a very high FDA-recommended level of sterility and our staff working in these laboratories are working in one of the cleanest and safest environments on the planet.  We have been working at this level for more than a decade.

We will be monitoring the CDC and the AVMA alerts and keep all of you up to date with any new or changed information regarding COVID-19 and veterinary medicine.

Reputable sources for information:

• CDC information on animals and COVID-19 click here
• CDC info on people with COVID-19 in home care with pets click here
• AVMA resources on pets and COVID-19 click here

Be safe.

Bob Harman, DVM, MPVM

Today is National K9 Veterans Day, an unofficial holiday where we commemorate the service and sacrifices of all United States military and working dogs.  It was on March 13, 1942 that dogs first began training for the new War Dog program, and officially became a part of the U.S. Armed Forces.

VetStem has a bit of history with a famous K9 Veteran.  Though he is now deceased, Lex’s story was shared far and wide, a real tearjerker.  We have shared this story before, but we believe it deserves to be shared again. 

Lex was a bomb-sniffing German shepherd who served two tours in Iraq.  In 2007, Lex was on duty in Iraq with his handler and best friend, 20-year-old Corporal Dustin Lee.  On March 21, 2007, Cpl. Lee’s base was attacked, and a 73 mm rocket explosion killed Cpl. Lee.  Lex was also injured in the attack however was said to have laid upon Cpl. Lee in an attempt to protect him.  Later, it was said that Lex had to be pulled away from Cpl. Lee to allow medics to attend to him.  Unfortunately, Cpl. Dustin Lee succumbed to his injuries and passed away shortly after being taken to a nearby hospital.  This was just six weeks before Cpl. Lee was scheduled to return home.

Lex also sustained injuries in the attack.  His fur was burned and shrapnel was lodged in his back and spine.  After returning home and attending the funeral of his friend Cpl. Lee, Lex returned to duty at the Marine Corps base in Georgia.  Cpl. Lee’s family however lobbied for months to adopt Lex and in December 2007, Lex was officially discharged from the U.S. Marine Corps and taken home to his new family in Mississippi.

But Lex’s story doesn’t end there.  Due to his injuries and the shrapnel that was still lodged in his body, Lex developed degenerative joint disease.  His osteoarthritis became a problem, causing pain and mobility issues.  That’s where VetStem comes in.  Lex was taken to Dr. Lee Morgan of Georgetown Veterinary Hospital who recommended treatment with VetStem Cell Therapy.  In 2010, Lex received injections of his own stem cells in his left hip and knee as well as intravenously.  Lex initially had a great response to treatment and regained the ability go up stairs.

In addition to Lex, VetStem has provided stem cell therapy services for several law enforcement and search and rescue dogs.  Though their stories may not be as dramatic as Lex’s, working dogs face rigorous physical activity and the potential for injury while on the job or later down the line after years of wear and tear on their joints.  Just like their two-legged partners, they are willing to sacrifice it all for the safety of others.  And for that, we honor all K9 veterans and working dogs alike.

At just 14 weeks old, Trusty walked with a slight limp and had difficulty with stairs.  Even for a purebred Greater Swiss Mountain Dog, he was large for his breed.  As he grew, his limp continued to worsen, and it was obvious he was in pain.  This was especially problematic because Trusty lives on a 40-acre apple orchard in the Pacific Northwest with his human family and several other active dogs.

Diagnosing Trusty’s leg issue proved to be very difficult.  After 10 travel appointments, X-rays, CT scans and ultrasounds, Trusty was eventually referred to veterinary surgeon Dr. Kristin Kirkby Shaw of Animal Surgical Clinic of Seattle.  After additional imaging and arthroscopy, Dr. Kirkby Shaw diagnosed Trusty with Fragmented Coronoid Process (FCP) and osteoarthritis of the left elbow.  She recommended surgery in addition to treatment with VetStem Regenerative Cell Therapy.  

In August 2019, Trusty received an injection of his own stem cells into his ailing left elbow.  According to his owner, Trusty recovered almost immediately from his surgery and was walking without a limp at two weeks post-surgery.  Approximately six weeks after the procedure, Trusty was feeling great and running around the property, playing with his dog siblings.  Trusty’s owner stated, “It’s really the first time in his life he has been able to run! We are very happy for him, thankful to Dr. Kirkby Shaw for her skills and knowledge and to VetStem Biopharma for providing us with this tremendous healing technology which we know has been a huge factor in Trusty’s recovery.”

Trusty’s stem cell success story is reminiscent of Sheldon’s, who also received VetStem Cell Therapy for osteoarthritis related to FCP.  Unfortunately, this condition is not uncommon in large breed dogs such as Trusty and Sheldon.  If your dog has been diagnosed with FCP or osteoarthritis, speak to your veterinarian about the possibility of treating your dog with VetStem Cell Therapy.  Or contact us to receive a list of VetStem providers in your area.

Did you know that February is both spay and neuter awareness month as well as pet dental health month?  These procedures all require that your dog go under general anesthesia.  Since collecting fat for stem cell therapy also requires anesthesia, why not combine the two?

If your dog is undergoing anesthesia for a routine surgical procedure such as a spay, neuter, or dental cleaning, you should consider asking your veterinarian to collect fat at the same time.  This fat can be used to provide stem cell treatment for your dog in approximately 48 hours or it can be stored for potential future use.

At VetStem, we provide a service called StemInsure.  We like to think of it as the “Stem Cell Insurance” for dogs.  For a StemInsure, your veterinarian will collect a small sample of fat tissue from your dog and will ship it to the VetStem laboratory.  VetStem lab technicians will process your dog’s fat to isolate the stem cells and cryopreserve them for potential future use.

This process can be beneficial for certain breeds of puppies who are likely to develop orthopedic conditions as they age.  Or it may be useful for dogs who have other health concerns and it is therefore ideal to minimize the number and length of anesthetic procedures.

Learn more about the canine StemInsure here or contact us for a list of VetStem providers in your area.

Jesse, a Spanish Arabian, was 11 years old when he suddenly went lame.  A bone scan and MRI revealed a severe injury to his right front deep digital flexor tendon.  The diagnosing veterinarian, Dr. Mark Martinelli of California Equine Orthopedics, recommended treatment with VetStem Cell Therapy and also referred Jesse to Dr. Sylvia Ouellette who specializes in equine lameness diagnosis and treatment.

Jesse began a long rehabilitation process with Dr. Ouellette.  During rehab he experienced another setback, after which Jesse’s owner pursued treatment with stem cells.  Jesse received one injection of his own stem cells into his injured tendon, but he wasn’t out of the woods yet.

Jesse continued with a rigorous rehabilitation schedule and experienced a few setbacks.  It was two years after his initial injury when Jesse’s owner finally received the good news that Jesse was sound.

Jesse was initially treated with VetStem Cell Therapy back in May 2006- almost 14 years ago!  Yet in a recent update from Jesse’s owner, Jesse is now 24 years old and his tendon has remained sound. Jesse’s owner stated, “Though he has other age-related health issues, the deep flexor tendon has stayed strong and has served him well all of these years.”   

Jesse is not the only horse to receive lasting effects from stem cell therapy.  Another horse, CP Merritt, was still competing at a champion level after receiving VetStem Cell Therapy 10 years prior.

If you think your horse may benefit from stem cell therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

Patients with compromised mobility due to osteoarthritis or acute orthopedic injuries are often prescribed physical rehabilitation.  Physical rehabilitation or physical therapy (PT) refers to a number of non-invasive techniques including but not limited to exercise, manipulation, cold therapy, heat therapy and electrotherapy.  The goal of PT is to reduce pain and improve strength and mobility and thereby, improve a pet’s quality of life.

Physical therapy can also be a great way to help a pet recover from surgery.  When used postoperatively, the goal is to decrease pain, inflammation, and recovery time.  When applied appropriately, these treatments may have both immediate and long-term effects.  For these reasons, VetStem recommends that pets follow some basic rehabilitation guidelines after receiving intra-articular (into the joint) or intra-lesional (into the injured tissue) stem cell injections.

Though the optimal post-stem cell injection rehabilitation protocol is unknown, your veterinarian can help you craft a rehab routine that is based on your pet’s specific condition and needs.  Some factors that may affect your pet’s rehabilitation protocol include severity of the condition, number of joints/lesions that are affected and/or injected, as well as other medical conditions your pet may have. In general, VetStem recommends starting with very light rehabilitative exercises for the first several weeks following stem cell therapy.  For dogs and cats, this may include passive range of motion and stretching as well as slow leash walks.  For horses this may include limited or short hand walks or stall rest with hand grazing, depending on the condition being treated.  We understand keeping a pet quiet can be challenging for many owners.  We believe however that it is very important to follow good rehabilitation practices to help your pet heal in the most optimal way. Patience and good nursing care can help your pet’s healing process in both the short and long term.        

As we close out the first month of 2020, we wanted to share some highlights from 2019.  Here is VetStem’s 2019 year in review.

In 2019:

• VetStem provided stem cell processing services for over 800 patients.

• We trained over 60 new veterinarians to use VetStem Cell Therapy.

• Over 80 veterinarians began using VetStem services and/or products for the first time.

• We processed fat tissue from more cats in 2019 than we have in any one year out of the entire ten years that we’ve been providing this therapy for cats.  This is likely due to the launch of our Clinical Research Programs including feline Chronic Kidney Disease, Gingivostomatitis, and Inflammatory Bowel Disease.

• We provided stem cell services for the first bear to be treated with VetStem Cell Therapy.

• Along those same lines, we donated a platelet therapy kit for the treatment of our first kangaroo.

• VetStem was featured in an award-winning documentary, Animal Pharm: Where Beasts Meet Biotech.

• VetStem entered the pet cancer field with new work on a developing cancer therapy. 

• And perhaps most important, in 2019, VetStem announced the launch of our human stem cell company, Personalized Stem Cells, Inc. who is currently conducting an FDA-approved clinical trial for the treatment of knee osteoarthritis with stem cells.

WHEW!  It was a big year for us!  Thank you to our veterinary colleagues and pet owners who have entrusted us with the processing of your patient’s and pet’s stem cells.  Here’s to a great 2020 for everyone! 

At just four months old, Tucker, a Labrador retriever, was limping and lame.  At one year of age, he was diagnosed with bilateral hip and elbow dysplasia.  His veterinarian prescribed him pain medications as well as nonsteroidal anti-inflammatories (NSAIDs).  After four years of continuous medication and restricted physical activity, Tucker’s owners were introduced to VetStem Regenerative Cell Therapy as a potential treatment option for osteoarthritis in his hips and elbows.

To begin the process, Dr. Glenn Behan of Barnegat Animal Clinic collected Tucker’s fat tissue and sent it off to the VetStem laboratory in January 2019. Once received, VetStem lab technicians processed the fat to extract Tucker’s stem and regenerative cells for injectable stem cell doses. Tucker’s stem cell injections were sent back to Dr. Behan and, approximately 48 hours after the initial fat collection, Tucker received one injection into each hip and each elbow.

At just one month post stem cell therapy, Tucker’s owners noticed his energy level was up, he could get up and down with more ease, and stairs were easier to climb. After approximately six weeks, Tucker could walk further distances and his limp subsided. His owner stated, “He was able to actually run on the beach and through the surf for the first time without pain. There was almost a hop in his step which we had never seen before.”  In a 90-day follow up survey, Tucker’s owner reported that he was able to discontinue his pain and anti-inflammatory medication and his quality of life was significantly improved.

Approximately seven months post stem cell therapy, Tucker continued to do great. With his increased activity, he lost ten pounds and was getting around so much better. He would go on walks, up and down stairs and even began jumping on the bed, which he could not do before. He also played a lot more with his little brother. At that point in time, he continued to not require pain or anti-inflammatory medication.

It has been approximately one year since Tucker’s stem cell therapy and he has not required additional stem cell treatments.  Like Tucker, some dogs are able to reduce or discontinue pain and/or anti-inflammatory medications after receiving VetStem Regenerative Cell Therapy.  It is important to point out that NSAID use can lead to gastrointestinal upset and organ damage, which is why most veterinarians advise against long-term use of NSAIDs.

If you think your dog may benefit from stem cell therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

At VetStem, one of our goals is to educate pet owners about the prevalence and potential severity of osteoarthritis (OA) in our pets.  Osteoarthritis is a degenerative disease that can be debilitating.  It has even been identified as the number 2 reason for euthanasia.  Though 1 in 5 dogs in the U.S. are affected by OA, there are some steps you can take to potentially reduce or delay the symptoms of OA in your pet. 

In a previous blog, we shared some steps you can take to help reduce or delay the symptoms of OA in your pet.  One of those steps is to provide your pet with regular exercise.  While pets require varying amounts and different types of exercise, your veterinarian can help you to develop an exercise routine tailored specifically to your pet.

Since January is Walk Your Pet month, we thought it important to highlight the potential effects that regular walks can have on your pet’s joint health.  Colorado State University College of Veterinary Medicine states, “Regular physical activity is paramount in the treatment of osteoarthritis both in humans and animals.  A lifestyle of regular activity that is moderated away from intermittent extremes of exercise and activities to which the pet is not conditioned is essential.  Ideally, multiple shorter walks are better than one long one.  The same activity every day (or slightly increasing if tolerated) is ideal.” 

According to the Arthritis Foundation, walking comes with several benefits which may lead to healthier joints including muscle strengthening, joint fluid circulation, and weight loss.  Weight loss is an important factor when it comes to managing pain and lameness associated with osteoarthritis.  One study found that weight loss significantly decreased lameness in obese dogs with OA.  If you’re concerned that your pet may be overweight, you can refer to this blog or contact your veterinarian. And don’t forget, cats get OA too!  Cats with OA may also benefit from exercise.  Speak to your veterinarian about the best way to exercise your cat.