Immune-mediated diseases occur when the body’s immune system mistakenly attacks its own healthy tissues, leading to inflammation and disease-related side effects. In dogs and cats, these conditions can affect many parts of the body, including the joints, skin, intestines, blood cells, and more. Common examples include inflammatory bowel disease (IBD), immune-mediated polyarthritis (IMPA), feline chronic gingivostomatitis, and certain inflammatory skin conditions. While traditional treatment often relies on immunosuppressive medications such as steroids, some pets continue to experience persistent symptoms or medication-related side effects.

Stem cell therapy is emerging as a promising regenerative medicine option for select immune-mediated conditions because of the unique immunomodulatory properties of mesenchymal stem cells. Rather than simply replacing damaged tissue, these cells help regulate the immune response by reducing excessive inflammation and promoting a healthier balance within the immune system. This may help decrease ongoing tissue damage while supporting the body’s natural healing processes. Research has demonstrated that mesenchymal stem cells can influence the activity of multiple immune cell types, making them an area of growing interest for a variety of inflammatory and immune-mediated diseases.

One of the most promising veterinary applications is inflammatory bowel disease (IBD) in dogs and cats. Studies have reported improvements in clinical signs, including reduced vomiting and diarrhea, weight gain, and improved quality of life following stem cell therapy. At VetStem, we have also seen encouraging outcomes in pets with IBD and other immune-mediated conditions, particularly those that have not responded well to conventional treatments alone. While stem cell therapy is not considered a cure, it may provide meaningful improvement for carefully selected patients when incorporated into a comprehensive treatment plan.

As research into regenerative medicine continues to expand, stem cell therapy may become an increasingly valuable tool for managing immune-mediated diseases in veterinary medicine. By helping regulate the immune system rather than simply suppressing it, stem cells offer a different approach to treating chronic inflammatory conditions. If your pet has been diagnosed with an immune-mediated disease, talk with your veterinarian to determine whether VetStem Cell Therapy may be an appropriate addition to their treatment plan. You can also contact us to find a VetStem provider near you.

Shoulder injuries are a common cause of front limb lameness in dogs, particularly active and sporting breeds. One of the most frequently affected structures is the biceps tendon, which helps stabilize the shoulder joint and flex the elbow. Because tendons have a limited blood supply, they tend to heal slowly, and chronic inflammation can lead to persistent pain and reduced function. While rest, rehabilitation, and anti-inflammatory medications may provide relief, some dogs continue to experience lameness despite conservative treatment.

For these challenging cases, regenerative medicine may offer another option. VetStem Cell Therapy utilizes a dog’s own adipose-derived stem and regenerative cells, which are processed from a small sample of fat tissue and injected into the injured area. These cells have shown to downregulate inflammation, support tissue regeneration, and promote healing.

Published research provides encouraging evidence for the use of adipose-derived stem cells in tendon injuries across multiple species. In one retrospective study of 55 dogs with supraspinatus tendinopathy (a shoulder tendon injury similar in nature to biceps tendinopathy) dogs treated with adipose-derived regenerative cells combined with platelet-rich plasma (PRP) demonstrated significant improvements in limb function and ultrasound appearance of the tendon. Ninety days after treatment, 88% of dogs showed normal limb function, and ultrasound exams revealed healthier tendon tissue and reduced swelling.

At VetStem, we have treated numerous dogs with biceps tendon injuries as part of a comprehensive treatment plan developed by their veterinarian. While every patient is unique, stem cell therapy is often considered alongside rehabilitation and other treatment modalities to help support tendon healing and improve comfort. Think your pet may benefit from VetStem Cell Therapy? Contact us to receive a list of providers near you.

For active dogs, orthopedic injuries can happen more than once over a lifetime. Sunny, a young, energetic Labrador retriever, is a perfect example. After partially tearing his cruciate ligament and being diagnosed with luxating patellas in both knees, Sunny’s veterinarian, Dr. Kim Carlson of Lenity Vet Specialists and Emergency Care, recommended VetStem Cell Therapy in conjunction with TPLO surgery. Having previously seen the success of VetStem Cell Therapy with their other Labrador, Lucky, who was treated for elbow dysplasia, Sunny’s owners felt confident moving forward with regenerative medicine once again.

During the procedure, a small sample of fat was collected from Sunny’s abdomen and sent to the VetStem laboratory, where his stem and regenerative cells were processed. Several doses were prepared for immediate treatment while the remaining cells were cryopreserved, or banked, for future use. Sunny received stem cell injections in both knees, an intravenous dose, and preventative injections in his hips and elbows to help support long-term joint health.

Sunny recovered quickly from surgery, but his journey was far from over. Later, he developed a chronic wound that was slow to heal despite conventional treatments. Because his stem cells had been banked, Dr. Carlson was able to incorporate them into his treatment plan, and the wound ultimately healed after other therapies had provided limited improvement. Not long afterward, Sunny suffered another setback when he injured his right rear iliopsoas muscle, a painful injury that affected his ability to run, play, and even swim, his favorite activity.

Although laser therapy and other treatments provided little relief, Dr. Carlson once again turned to Sunny’s banked stem cells. The results were dramatic. Sunny’s owner stated, “I was skeptical, but literally within a week of the treatment, he was walking without shuffling, and a few weeks later, he was jumping around and playing like a puppy again, running full speed! I almost could not believe it!” After multiple surgeries and injuries, Sunny was finally able to return to the active lifestyle he loved, including getting back to the beach and the water.

Sunny’s story highlights one of the greatest advantages of VetStem Cell Therapy: cryopreservation of extra stem cells. Rather than undergoing another fat collection procedure each time a new injury occurred, his stored stem cells were readily available whenever they were needed. His owner summed it up best: “We are so glad we have stem cells banked for Sunny for his lifetime, since we have already used them several times in three years.” For young, active dogs that may experience multiple orthopedic injuries throughout their lives, VetStem Cell Therapy provides veterinarians and pet owners with a valuable regenerative medicine option that is ready when future needs arise.

Think your pet may benefit from VetStem Cell Therapy? Contact us to receive a list of VetStem providers near you.

Sunny

During National Farriers Week, we recognize the skilled professionals who play a vital role in equine health and performance. Farriers do much more than trim and shoe hooves. They are essential members of a horse’s healthcare team. Through regular hoof care, early detection of abnormalities, and collaboration with veterinarians, farriers help maintain proper balance, movement, and overall soundness in horses of all ages and disciplines.

At VetStem, we understand that optimal equine health often requires a multimodal approach. Just as farriers help support horses from the ground up, VetStem Cell Therapy can play an important role in addressing orthopedic conditions that affect mobility and performance. VetStem Cell Therapy has been used to treat horses with osteoarthritis, tendon injuries, and ligament injuries, helping many return to comfort and activity. In fact, according to VetStem survey data, 66% of horses treated for osteoarthritis returned to their previous level of performance, while 77% of horses with tendon injuries and 76% with ligament injuries did the same.

National Farriers Week is an opportunity to celebrate the partnership between farriers, veterinarians, trainers, and horse owners. By working together, these professionals help horses stay healthy, comfortable, and performing at their best. We thank farriers for their dedication, expertise, and commitment to equine welfare, and we are proud to support the collaborative care that helps horses thrive.

Dr. Jeff Christiansen of Superior Veterinary Surgical Solutions has been one of VetStem’s standout small animal practitioners for more than a decade. A board-certified veterinary surgeon, he first began incorporating VetStem Cell Therapy into his practice in 2012 and has now completed over 400 stem cell cases. That milestone reflects both his extensive experience and his long-standing commitment to bringing regenerative medicine into everyday clinical care.

Regenerative therapies are a key part of Dr. Christiansen’s treatment approach. He uses stem cell therapy alongside surgical procedures when appropriate, but also as a standalone option for non-surgical cases. While osteoarthritis and cruciate ligament injuries are common indications in his practice, his experience goes much further, including patellar instability, fractures, spinal disorders, kidney disease, and more complex conditions. His work has even extended beyond companion animals, including a collaboration with a local zoo where he used VetStem Cell Therapy to help improve mobility in an arthritic black bear.

He also frequently incorporates VetStem platelet-rich plasma (PRP) into his treatment plans, both for orthopedic and wound healing cases and in more unusual applications. From helping support fracture healing in a kangaroo to aiding recovery after tumor removal in an ostrich, his case history highlights just how versatile regenerative medicine can be. As Dr. Christiansen puts it, “I recommend stem cell therapy with any orthopedic surgery or as a treatment option for arthritis. I also recommend stem cell therapy for cases with spinal problems as well as for issues with kidneys and intestines.” His experience reflects a broader goal of improving comfort, mobility, and long-term quality of life for his patients.

Dr. Jeff Christiansen

Take Your Dog to Work Day is the perfect excuse to spend a little extra time with our four-legged best friends while recognizing the positive impact they can have in the workplace. While having dogs around certainly makes the office more fun, research suggests there may be real benefits as well. Studies have found that dog-friendly workplaces can help reduce stress, improve employee well-being, and increase job satisfaction. One review of workplace dog programs noted that dogs can contribute to a more positive work environment and support employee health and wellness.

Dogs may also help strengthen connections between coworkers. Research has shown that dogs in the workplace can encourage social interaction, boost morale, and create a greater sense of community among employees. Whether it’s stopping to say hello to a furry coworker, taking a quick walk outside, or sharing stories about our pets, dogs have a unique way of bringing people together and brightening the workday.

At VetStem, we are proud to be a dog-friendly workplace and enjoy these benefits every day. It’s not uncommon to see dogs making the rounds for treats and attention, relaxing beside their owners’ desks, or joining us for a walk during a break. Their presence helps create a welcoming, enjoyable atmosphere and serves as a daily reminder of why we’re so passionate about helping animals live happier, more comfortable lives. This Take Your Dog to Work Day, we’re celebrating all of the dogs who make our workplace a little brighter.

Mick, VetStem CEO Dr. Bob Harman’s dog, enjoying a day at the office

June is recognized as National Zoo and Aquarium Month, a time to celebrate the important role accredited zoos and aquariums play in wildlife conservation, scientific research, and environmental education. Across the country, these organizations work tirelessly to protect endangered species, advance animal health, and inspire people of all ages to care about wildlife and the environment.

At VetStem, we are proud to support the health and well-being of animals in human care through regenerative veterinary medicine. Over the years, VetStem Cell Therapy has been used by multiple zoos and aquariums across the United States to help improve quality of life in a wide variety of exotic species. From large mammals and marine animals to birds and reptiles, veterinarians have utilized stem cell therapy to help manage orthopedic injuries, degenerative joint disease, and other painful conditions that can impact mobility and comfort.

Caring for exotic animals often comes with unique challenges, especially when it comes to age-related conditions and injuries. Maintaining mobility and reducing discomfort can make a significant difference in an animal’s daily activity and overall welfare. By partnering with zoological and aquarium veterinary teams, VetStem is honored to contribute to innovative treatment options that help support animal health and enhance quality of life.

This National Zoo and Aquarium Month, we celebrate the veterinarians, caretakers, researchers, and conservationists dedicated to protecting wildlife and providing exceptional care to the animals they serve. VetStem is grateful to play a small role in supporting these incredible efforts through regenerative medicine.

Brody, a young Florida Black Bear, received VetStem Cell Therapy for a condition similar to hip dysplasia in dogs.

Mr. Pickles, a boxer, was just four years old when he tore the cruciate ligament in his right knee, a painful injury that significantly affected both his mobility and quality of life. His veterinarian, Amie Csiszer of Oregon Veterinary Referral Associates, recommended surgery along with VetStem Cell Therapy to help support his recovery.

VetStem Cell Therapy has been used in thousands of animals to treat orthopedic injuries by helping reduce pain and inflammation while supporting the body’s natural healing process. When combined with surgery, stem cells can accelerate healing, minimize scar tissue formation, and potentially slow the progression of arthritis. This can lead to a reduction in symptoms and an overall improvement in quality of life.

According to his owner, Mr. Pickles healed quickly after surgery and stem cell treatment. Unfortunately, only a few months later, he tore the cruciate ligament in his other knee, something that’s actually very common in dogs with this injury. But this time, his family already had his stem cells banked and ready to use, allowing his veterinarian to move forward with treatment quickly. His owner shared, “This helped expedite Mr. Pickles’ healing and now down the road we have the cells stored. Very thankful for this service to support his wellbeing.”

Cruciate ligament tears are one of the leading causes of hind limb pain and lameness in dogs and often lead to arthritis over time, even after surgery. When used alongside surgical repair, VetStem Cell Therapy may help support healing, improve comfort, and potentially reduce the progression of arthritis. For Mr. Pickles and his family, having access to stem cell therapy provided added peace of mind during a challenging recovery journey.

If you think your dog may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

Mr. Pickles

Osteoarthritis (OA) in cats is far more common than many people realize, particularly as cats are living longer thanks to advances in veterinary medicine. OA is a degenerative joint disease in which the cartilage that cushions the joint gradually breaks down, causing inflammation, pain, decreased mobility, and permanent joint changes over time. While osteoarthritis is commonly recognized in dogs, it has historically been underdiagnosed in cats because felines are incredibly skilled at hiding discomfort. Unlike dogs, cats are naturally agile and lightweight, allowing them to compensate for joint pain more easily.

Recognizing OA in cats can be challenging because the signs are often subtle and very different from what owners expect. While limping is a hallmark sign of arthritis in dogs, many arthritic cats do not limp at all. Instead, they may become less active, hesitate to jump, groom themselves less, lose weight, act grumpier or quieter than usual, or begin urinating or defecating outside the litter box because climbing into the box becomes uncomfortable. In one study of cats with osteoarthritis, less than half of affected cats limped, while the majority showed reluctance to jump. Because these changes are often mistaken for “normal aging,” many cats suffer silently for years before receiving treatment.

Treatment options for feline osteoarthritis are also somewhat limited. Management often involves a multimodal approach that may include weight management, environmental modifications such as ramps or low-sided litter boxes, and rehabilitation therapies. However, unlike dogs, there are currently no FDA-approved veterinary NSAIDs for safe long-term control of osteoarthritis pain in cats, as cats are particularly sensitive to potential side effects from these medications.

For some feline patients, regenerative medicine may offer another option for osteoarthritis management. VetStem Cell Therapy utilizes a cat’s own stem cells to help reduce inflammation and pain and support joint health and mobility. The process involves collecting and processing a small sample of fat tissue, from which stem cells are extracted and prepared for treatment. Veterinarians may incorporate VetStem Cell Therapy into a multimodal OA management plan tailored to the individual cat. While every patient responds differently, many owners report improvements in mobility, activity level, and overall quality of life following treatment.

If you think our cat (or dog!) may benefit from VetStem Cell Therapy for arthritis, speak with your veterinarian or contact us to receive a list of VetStem providers near you.

Suspensory ligament injuries can be a serious setback for performance horses, often leading to prolonged discomfort and time away from work. For An Intimidating Zippo, a Quarter Horse gelding, that was exactly the challenge he faced after being diagnosed with a severe tear in his left hind suspensory ligament, spanning Zones 1 through 3. Injuries of this magnitude can significantly impact mobility and long-term soundness, making effective treatment essential for both recovery and quality of life.

To help support healing, his veterinarian recommended VetStem Cell Therapy. Following treatment and a structured rehabilitation program, An Intimidating Zippo’s owner reported an excellent outcome, noting that the ligament healed completely. His case highlights the potential of stem cell therapy to aid in the repair of soft tissue injuries that are traditionally difficult to manage. Even when he was later diagnosed with mild Degenerative Suspensory Ligament Desmitis (DSLD) in both hind limbs, his veterinary team had a proactive plan in place to utilize his banked stem cells to support ongoing ligament health and comfort through annual treatments.

Stem cells are powerful regenerative cells known for their ability to reduce inflammation, decrease pain, minimize scar tissue formation, and promote the repair of damaged tissues such as ligaments and tendons. These properties make VetStem Cell Therapy a valuable option for equine orthopedic conditions. As a pioneer in veterinary regenerative medicine, VetStem has treated thousands of horses since 2004, with survey data showing that many are able to return to their previous level of work following treatment. Cases like An Intimidating Zippo demonstrate how regenerative therapies can play an important role in helping horses recover, maintain performance, and enjoy a better quality of life.

If you think your horse may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us for a list of VetStem providers near you.

An Intimidating Zippo