We frequently hear about osteoarthritis (OA) in dogs. And for good reason! OA affects approximately 1 in 5 dogs and can greatly reduce a dog’s quality of life. What we don’t hear about as much is osteoarthritis in cats. But, perhaps surprisingly, a high percentage of cats are affected by OA. In fact, according to one study, 91% of cats between 6 months and 20 years old have OA in at least one joint, as proven by X-rays.

Recognizing Arthritis in Cats

Unlike dogs, cats with pain from arthritis do not typically present with symptoms like limping and lameness. Instead, they will be less willing to jump and/or have shorter jumps. You may also notice a loss of appetite and weight loss, depression or a change in general attitude, poor grooming habits, and urination or defecation outside the litter box.

Case Report: Clyde’s Treatment with VetStem Cell Therapy

One example is Clyde, a cat who suffered from arthritis in multiple joints. According to his owner he could not go up and down stairs, his coat was unkempt, and he no longer climbed in the cat tree. His veterinarian recommended treatment with VetStem Cell Therapy. At the time of treatment, Clyde was approximately 15 years old.

To begin the process, Clyde’s veterinarian collected fat during a minimally invasive anesthetic procedure. The fat was shipped to VetStem where it was processed in our laboratory to extract and concentrate Clyde’s stem cells. One dose of Clyde’s own stem cells was shipped back to his veterinarian for intravenous treatment.

Clyde responded wonderfully to VetStem Cell Therapy. According to his owner, he was able to run up and down the stairs and enjoyed playing with his cat siblings. He also began climbing the cat tree again to watch the birds. Additionally, both his appetite and grooming improved, his coat became shiny and smooth once again.

The Important of Regular Vet Visits for Cats

In this instance, Clyde had symptoms that led his owner to pursue veterinary care. But many cats are masters at hiding their pain. As we approach National Take Your Cat to the Vet Day next week, this is a good reminder that cats need routine veterinary care just as much as dogs. And if you think your cat may benefit from treatment with VetStem Cell Therapy, contact us to receive a list of VetStem providers near you.

Clyde

As most of our readers know, VetStem Cell Therapy is primarily used to treat orthopedic conditions in dogs and horses. Cats, on the other hand, frequently receive stem cell therapy for indications such as renal disease, inflammatory bowel disease, and gingivostomatitis. One such cat, a young Siamese named Finn, received VetStem Cell Therapy for gingivostomatitis when he was approximately one year old.

We’ve shared Finn’s stem cell success story in a previous blog. But to sum it up, Finn was diagnosed with gingivostomatitis at just five months old. Gingivostomatitis is a debilitating condition characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduced grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, pain medications, and/or full mouth teeth extractions.

Finn’s owners tried several medications in an effort to improve his symptoms, but nothing worked. They were determined to not have all of his teeth extracted and were willing to do whatever it took. His veterinarian recommended treatment with VetStem Cell Therapy and just shy of his first birthday, Finn received stem cell therapy.

According to his owners, Finn responded well to the treatment. His owner stated, “[the stem cell treatment] seemed to improve and maintain his condition especially over time so that Finn is happy, healthy, and living a great life. We plan to administer cells every year or so to keep his condition manageable and hopefully keep him healthier too.”

Fast forward to the present, four years after his initial stem cell treatment, and Finn continues to do well! We recently received an update from his owner who stated, “Finn had his annual checkup recently and he’s doing great. He had some gingivitis but his stomatitis seemed to be under control. He had his annual teeth cleaning today (per his veterinarian’s recommendation) and is doing great otherwise!”

Stem cells have shown the ability to reduce inflammation and also help to modulate the immune system. This mechanism of action is particularly important for immune-mediated conditions such as gingivostomatitis. If your cat has gingivostomatitis, VetStem Cell Therapy may help. Contact us to receive a list of providers near you.

National Cat Day is fast approaching, and we never miss an opportunity to talk about VetStem Cell Therapy for cats. While stem cells are primarily used for orthopedic conditions, many veterinarians have used VetStem Cell Therapy to help treat and control symptoms associated with diseases such as kidney disease, gingivostomatitis, and inflammatory bowel disease.
All three of these diseases are prevalent in cats and have limited treatment options.

Stem Cells for Kidney Disease

Kidney disease is one of the most common causes of sickness and death in cats. Common symptoms can include weight loss, lethargy, variable appetite, and poor coat quality. Some cats may also drink and urinate more, vomit, or have diarrhea.Unfortunately, treatment options for cats with kidney disease are limited and can be costly.

The good news is, based upon our own data as well as the data of others, we believe that stem cells may help improve the symptoms and quality of life in some cats with kidney disease. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment. Owners and veterinarians have also reported improved appetites, weight gain, and increased energy in cats treated with VetStem Cell Therapy.

Stem Cells for Gingivostomatitis

Gingivostomatitis is another debilitating condition found in cats. It is characterized by chronic inflammation of the gums, which can lead to inappetence, reduce grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, and pain medications and/or full mouth teeth extractions.

A recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. Additionally, veterinarians and cat owners have reported an improvement in symptoms and quality of life in cats treated with VetStem Cell Therapy.

Stem Cells for Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is an intestinal disorder that affects both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Multiple cats have received VetStem Cell Therapy for IBD (dogs too!). And we have had reports from veterinarians and owners regarding the improvement of their patients and pets after treatment with stem cells. Additionally, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

If you think your cat may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

In last week’s blog, we discussed kidney disease in cats and how VetStem Cell Therapy may help. This week, we want to discuss osteoarthritis (OA) in cats so that cat owners know what to watch out for. That’s right, cats get OA too! In fact, a high percentage of cats will get or already have osteoarthritis. According to one study, 91% of cats between 6 months and 20 years old have OA in at least one joint, as proven by X-rays.

National Take your Cat to the Vet Day

But why two cat blogs in a row, you ask? Well August 22^nd is National Take your Cat the Vet Day. This day is meant to bring awareness to the fact that the statistics for feline veterinary care are disparagingly low compared to dogs. According to one recent academic survey, only 20% of cat owners said they took their cat to the vet more than once a year, compared to 35% of dog owners. Additionally, 7% of cat owners said they never seek veterinary care, compared to 2% of dog owners. Likewise, in a targeted survey of pet owners conducted by the AVMA, only 48% of cat owners said they sought routine veterinary care for their cat, compared to 79% of dog owners.

Cats are Masters at Hiding Their Pain

There are likely several reasons for this discrepancy, one of which may be the fact that cats tend to be masters at hiding their pain. This tendency is often linked to survival instincts. In the wild, if a cat shows weakness, this may draw unwanted attention from a predator. But in the domestic cat whose only predator is a half empty bowl of food, this tendency to hide pain just means us owners have a hard time knowing when our cat should be taken to the vet.

Preventative Veterinary Care for Cats

Thus, National Take your Cat to the Vet Day promotes the idea of once-to-twice yearly preventative veterinary exams. These types of routine check-ups are important to maintain a cat’s health. Even if nothing appears to be wrong with your cat, routine examinations by your veterinarian may uncover some ailment that your cat has been hiding. In the same way, routine bloodwork can help your veterinarian monitor for diseases such as kidney failure.

Symptoms of Osteoarthritis in Cats

But back to OA in cats. For years, osteoarthritis in cats has been underdiagnosed when compared to dogs. One reason for this is that cats with OA present with different symptoms than what we see in dogs. Because of their smaller size and natural agility, cats tend to tolerate bone and joint problems better than dogs. But there are specific symptoms to watch out for.

According to the FDA, “Clinical signs of osteoarthritis in cats include weight loss, loss of appetite, depression, change in general attitude, poor grooming habits, urination or defecation outside the litter pan, and inability to jump on and off objects.” Unlike dogs, cats do not commonly present with lameness or limping. Instead, they will be less willing to jump and/or have shorter jumps.

Treatment for Osteoarthritis in Cats

Unfortunately, there are fewer treatment options for cats with OA compared to dogs. Unlike dogs, cats do not tolerate nonsteroidal anti-inflammatory drugs (NSAIDs) or other pain medications very well. While there are some NSAIDs approved for short-term post-operative use in cats, there are currently no veterinary NSAIDs approved for safe, long-term use to control osteoarthritis pain in cats. There are some non-drug options including weight loss for overweight cats, increased exercise, as well as environmental accommodations such as elevated food bowls and more easily accessible litter boxes. But these are not the only non-drug treatment options available.

VetStem Cell Therapy for Osteoarthritis in Cats

VetStem Cell Therapy is a non-drug treatment option for osteoarthritis in cats, dogs, and horses. It can be particularly beneficial for cats, given that effective treatment options to control osteoarthritis pain are extremely limited. Stem cells have shown the ability to directly modulate pain and down-regulate inflammation. Additionally, stem cells can induce repair and stimulate regeneration of cartilage and other joint tissues. The beauty of VetStem Cell Therapy is that we are harnessing your pet’s own healing power, so it can be considered a natural and holistic approach to managing the symptoms of osteoarthritis.

If you are interested in having your pet treated with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

VetStem Cell Therapy, while commonly used to treat orthopedic conditions in dogs and horses, has also been successfully used to treat a number of other diseases. One such disease is kidney disease in cats. Nearly 250 cats have received VetStem Cell Therapy for kidney disease.

Kidney disease is one of the most common causes of sickness and death in cats. Common symptoms can include weight loss, lethargy, variable appetite, and poor coat quality. Some cats may also drink and urinate more, vomit, or have diarrhea.

Unfortunately, treatment options for cats with kidney disease are limited and can be costly. The good news is, based upon our own data as well as the data of others, we believe that stem cells may help improve the symptoms and quality of life in some cats with kidney disease. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment.

Anecdotal data from pet owners and veterinarians suggests that treatment with VetStem Cell Therapy helps to improve symptoms associated with kidney disease. Owners have reported improved appetites, weight gain, and increased energy. That being said, more data is necessary regarding the use of VetStem Cell Therapy for cats with kidney disease. Thus, we continue to research the use of stem cells for this condition under one of VetStem’s clinical research programs.

If you think your cat may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of qualified VetStem providers near you.

Hi all! Veronika here, VetStem’s Customer Service Manager. I’m taking over the blog this week to tell you the story of Gryffin, my cat who received VetStem Cell Therapy for inflammatory bowel disease. Gryffin is an eleven-year-old Ragdoll who rules our house! He has many nicknames including Gryffindorable and the Handsomest of Handsomes! If you haven’t guessed, he has me wrapped around his little fluffy paw.

But recently, he has been experiencing some symptoms that warranted a trip to the vet. My normally floofy boy lost a lot of his beautiful coat. He was vomiting 2-3 times a week, had a reduced appetite and weight loss. Though normally full of catitude, he was acting lethargic and not playing or engaging much with the family or my crazy Frenchie, Darby, and was often isolating.

Gryffin was diagnosed with inflammatory bowel disease (IBD). IBD is a gastrointestinal disease that can affect both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. Numerous cats have received VetStem Cell Therapy for IBD and I’ve heard great results firsthand from some of their owners so I knew exactly what I needed to do.

Gryffin received his first stem cell treatment in February. About a week after that first intravenous injection, I noticed small positive changes. His appetite increased and he was generally a little more upbeat. He was coming out of his shell a little bit and even started climbing to the top of his cat tree again.

He received a second intravenous stem cell treatment in early March, three weeks after his first treatment. That is when I began to notice more obvious improvements. He now voluntarily plays (by himself or with us). He’s also begun doing “racetrack” around the house again and annoying Darby. His stools have firmed up and he has not vomited in probably a month or more. I even bought him $30 worth of cat toys because I was so excited he wants to play again! His coat has started to come back and he has gained some weight.

I know without a doubt that stem cells helped my sweet boy feel better. I’m so fortunate to work for VetStem and to know about this amazing technology. I want to spread the word to all pet owners who are dealing with IBD, which can be such a frustrating and debilitating disease. If you think VetStem might help your furry friend, don’t hesitate to reach out! You can bring it up to your veterinarian (print out this blog if you want!) or use our Locate a Vet page to find a VetStem vet near you: https://vetstem.com/locatevet.php.  

Check out a video of Gryffin playing with his toy mouse now that he’s feeling better:

While VetStem Cell Therapy is primarily used to treat orthopedic conditions, many patients have received stem cell therapy for alternate indications such as kidney disease, gingivostomatitis, and inflammatory bowel disease. Conditions such as these are still in the investigational stage, as there is minimal published data to demonstrate that stem cells are effective in treating these diseases.

That being said, it is well documented that stem cells have anti-inflammatory properties, which, theoretically, may make them effective at treating a wide range of inflammatory diseases and processes. One example of an inflammatory disease is feline asthma.

Asthma is defined as a chronic inflammatory process involving the tracheal, bronchi, and lung fields. Cats with asthma often have a chronic cough, acute respiratory distress, and vomiting. There is currently no cure for feline asthma so traditional treatment is focused on managing the disease with oxygen, inhalers, and steroids. As one can imagine, getting a cat to cooperate with using an inhaler is not always easy. And long-term steroid use comes with several negative side effects.

That’s where VetStem Cell Therapy comes in. Stem cells have the ability to home to areas of inflammation and down-regulate that inflammation. Not only can they control inflammatory processes, stem cells can also modulate the immune system, which may play a role in reducing the number of acute asthmatic episodes in an affected cat. Some cats have received VetStem Cell Therapy for asthma, and while much of the evidence is anecdotal at this point, we have received reports of improvement in symptoms and one case where the cat went into complete remission. That being said, we still have much to learn about using VetStem Cell Therapy to treat feline asthma. And it is important to note that every patient reacts differently to treatment with stem cells.  

Tomorrow is National Cat Day and what perfect timing since our sales and marketing team is currently at the annual American Association of Feline Practitioners (AAFP) conference! For the past few years, VetStem has been a bronze sponsor at this conference and has delivered a talk on the topic of VetStem Cell Therapy for cats to veterinarians and veterinary technicians.

This year, VetStem’s very own Dr. Anne Hale will be delivering a talk entitled Evidence Based Medicine Supporting Stem Cell Therapy in the Feline Patient. In her talk, Dr. Hale will discuss the potential uses of VetStem Cell Therapy in cats. As many of you know, veterinarians have used stem cells to treat renal disease, both acute and chronic, inflammatory bowel disease, gingivostomatitis, and more in cats. This year, Dr. Hale will also introduce a few feline clinical trials that VetStem will be enrolling for soon.

We find AAFP to be one of our favorite shows. From the attendees to the educational offerings, this show has a lot to offer. Feline medicine is unique in the field of veterinary medicine. For a long time, cats were often treated like small dogs. However, there are several physical and physiological differences between cats and dogs that are important to understand from a caregiving standpoint.

One major difference is that cats metabolize drugs very differently than dogs. This is why there are limited treatment options when it comes to pain in cats. While dogs tend to tolerate NSAIDs and other pain medications relatively well, cats do not. There are some NSAIDs approved for short-term post-operative use in cats, but there are currently no veterinary NSAIDs approved for safe, long-term use to control osteoarthritis pain in cats.

This is one of the reasons that technologies such as VetStem Cell Therapy are so important in feline medicine. Stem cells can help control pain and inflammation, can regulate the immune system, and can help regenerate damaged tissues. This makes stem cell therapy a potential treatment option for a wide array of diseases that are lacking effective treatment protocols in cats.

If you think your cat may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to find a VetStem provider near you.

August 22nd is National Take Your Cat to the Vet Day. We like to bring attention to this matter because the statistics for feline veterinary care are disparagingly low compared to dogs. According to one recent academic survey, only 20% of cat owners said they took their cat to the vet more than once a year, compared to 35% of dog owners. Additionally, 7% of cat owners said they never seek veterinary care, compared to 2% of dog owners. Likewise, in a targeted survey of pet owners conducted by the AVMA, only 48% of cat owners said they sought routine veterinary care for their cat, compared to 79% of dog owners. For the purpose of this blog, we will discuss feline osteoarthritis and why routine veterinary care is so important when it comes to managing this disease.

Cats Get Arthritis Too

It may surprise some to learn that a high percentage of cats will get or already have osteoarthritis (OA). According to one study, 91% of cats between 6 months and 20 years old have OA in at least one joint, as proven by X-rays. That being said, sometimes cats with OA have no visible changes on the X-rays. This is one of several reasons why osteoarthritis in cats can be difficult to diagnose.

Symptoms of Osteoarthritis in Cats

For years, osteoarthritis in cats has been underdiagnosed when compared to dogs. One reason for this is that cats with OA present with different symptoms than what we see in dogs. Because of their smaller size and natural agility, cats tend to tolerate bone and joint problems better than dogs. But there are specific symptoms to watch out for.

According to the FDA, “Clinical signs of osteoarthritis in cats include weight loss, loss of appetite, depression, change in general attitude, poor grooming habits, urination or defecation outside the litter pan, and inability to jump on and off objects.” Unlike dogs, cats do not commonly present with lameness or limping. Instead, they will be less willing to jump and/or have shorter jumps.

That being said, cats are masters at hiding their pain. Because it can be difficult to spot the signs of osteoarthritis in cats, routine veterinary care is essential. Your veterinarian will ask you questions about your cat’s behavior and will perform a comprehensive exam. Additionally, there are newer tools such as this checklist, that can help determine if your cat has OA.

Treatment for Osteoarthritis in Cats

Unfortunately, there are fewer treatment options for cats with osteoarthritis compared to dogs. Unlike dogs, cats do not tolerate nonsteroidal anti-inflammatory drugs (NSAIDs) or other pain medications very well. While there are some NSAIDs approved for short-term post-operative use in cats, there are currently no veterinary NSAIDs approved for safe, long-term use to control osteoarthritis pain in cats. There are some non-drug options including weight loss for overweight cats, increased exercise, as well as environmental accommodations such as elevated food bowls and more easily accessible litter boxes. But these are not the only non-drug treatment options available.

VetStem Cell Therapy for Osteoarthritis in Cats

VetStem Cell Therapy is a non-drug treatment option for osteoarthritis in cats, dogs, and horses. It can be particularly beneficial for cats, given that effective treatment options to control osteoarthritis pain are extremely limited. Stem cells have shown the ability to directly modulate pain and down-regulate inflammation. Additionally, stem cells can induce repair and stimulate regeneration of cartilage and other joint tissues. The beauty of VetStem Cell Therapy is that we are harnessing your pet’s own healing power, so it can be considered a natural and holistic approach to managing the symptoms of osteoarthritis.

If you are interested in having your pet treated with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

We’ve talked about treating feline gingivostomatitis with VetStem Cell Therapy a few times on this blog. But sometimes we need more than just the science to describe how this treatment can potentially help cats. So this time, we will share a success story. Finn is a Siamese cat with gingivostomatitis who experienced an improvement in his symptoms after treatment with VetStem Cell Therapy.

Gingivostomatitis Symptoms

At just five months old, Finn was diagnosed with gingivostomatitis. Gingivostomatitis is a debilitating condition characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduced grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, pain medications, and/or full mouth teeth extractions.

VetStem Cell Therapy for Gingivostomatitis

Current literature supports the notion that gingivostomatitis is an autoimmune disease. Mesenchymal stem cells have demonstrated the ability to migrate to areas of inflammation, down-regulate inflammation, modulate the immune system, stimulate neoangiogenesis (formation of new blood vessels), and repair damaged tissue. Additionally, a recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. While more research is needed, preliminary results suggest that VetStem Cell Therapy can improve the symptoms of some cats with gingivostomatitis.

Finn’s Treatment with VetStem Cell Therapy

Finn’s owners tried several medications in an effort to improve his symptoms, but nothing worked. They were determined to not have all of his teeth extracted and were willing to do whatever it took. His veterinarian recommended treatment with VetStem Cell Therapy and just shy of his first birthday, Finn received stem cell therapy.

To begin the process, fat was collected from Finn’s abdomen during a minimally invasive anesthetic procedure. The fat was sent to the VetStem processing laboratory. Lab technicians processed his fat to extract and concentrate his stem and regenerative cells and Finn received one intravenous injection of his own cells. Approximately four weeks later, Finn received a second intravenous dose using some of the stem cells banked from his initial fat collection.

According to his owners, Finn responded well to the treatment. His owner stated, “[the stem cell treatment] seemed to improve and maintain his condition especially over time so that Finn is happy, healthy, and living a great life. We plan to administer cells every year or so to keep his condition manageable and hopefully keep him healthier too.”

If your cat has gingivostomatitis, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy. Or contact us to receive a list of VetStem providers in your area.