Tomorrow is National French Bulldog Day! These snuggly, squished-face cuties have gained popularity in recent years but, as is the case with many purebred dogs, it’s important to note that they are susceptible to certain health conditions including spinal disorders. One of the most common neurological conditions affecting Frenchies is Intervertebral Disc Disease (IVDD).

IVDD is a degenerative condition that affects the spinal discs in dogs. In French Bulldogs, IVDD can be particularly problematic due to their unique body structure. With their short legs and long bodies, extra strain is placed on their intervertebral discs. When the discs become weakened or herniated, this causes compression on the surrounding nerves and/or spinal cord, which can lead to pain and mobility issues, including temporary or permanent paralysis.

Jojo

One example is Lady Josephine Beatrix Von Snugglebottom (aka Jojo). At just 6 months old, she was suffering from severe IVDD and spinal cord compression. At the time, she was unable to use her back legs for about one month. Jojo underwent surgery to relieve the pressure on her spine and aid in preventing further damage. She also received daily laser therapy and weekly acupuncture treatments. There was noticeable improvement in the strength in her legs, and she was able to hold herself up unassisted approximately two months after surgery. She still required a wheelchair however.

Shortly thereafter, Jojo was treated with VetStem Cell Therapy to aid the further healing of her spine. She received two intravenous injections of her own stem cells approximately one month apart. Her owner noted that following the treatment with stem cells, she was finally able to get around without her wheelchair. She began to run and, according to her owner, she hasn’t stopped since! Check out this adorable video of Jojo.

While many veterinarians have treated similar conditions with VetStem Cell Therapy and have seen remarkable results, it’s important to note that the research is ongoing for this condition and each dog will respond differently to treatment. A case such as Jojo’s falls under our Clinical Research Program for canine back pain. If you think your pet may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

January is Walk Your Pet Month, an opportune time to celebrate the numerous benefits that daily walks bring to our furry friends, particularly our canine companions. Regular walks play a crucial role in maintaining the overall well-being of our pets and can actually improve their joint health. You may be surprised to learn that walking can help manage the symptoms of and even delay the onset of osteoarthritis in dogs.

Osteoarthritis (OA) is a common ailment in dogs. According to the stats, 1 in 5 dogs in the U.S. are affected by OA, and it has been identified as a leading cause of euthanasia. Symptoms of OA include pain, reduced mobility, and a diminished quality of life.

Fortunately, walking can be a game-changer in mitigating these symptoms. Regular exercise helps our pets maintain a healthy weight, which alleviates stress on joints. Additionally, walking can help to strengthen the muscles and supporting soft tissue structures around the joints, promoting increased joint stability. It can also increase joint fluid circulation, which is beneficial to maintaining healthy joint cartilage.

According to Colorado State University College of Veterinary Medicine, “Regular physical activity is paramount in the treatment of osteoarthritis both in humans and animals. A lifestyle of regular activity that is moderated away from intermittent extremes of exercise (such as long hikes on the weekends) and activities to which the pet is not conditioned is essential. Ideally, multiple shorter walks are better than one long one. The same activity every day (or slightly increasing if tolerated) is ideal.”

That being said, all pets are different and what works for one dog may not work for another. Your veterinarian can help you craft an exercise regimen that is specifically tailored to your pet. And if your dog already suffers from OA, VetStem Cell Therapy may help get them back to their daily walks! Speak to your veterinarian or contact us to receive a list of providers near you.

We can hardly believe 2023 is coming to an end! This was an exciting year for VetStem. We launched a new product and spent much of the year promoting that product at numerous trade shows across the United States. As our final blog of the year, we wanted to share some highlights from the last 12 months at VetStem. So, without further ado, here is VetStem’s 2023 year in review!

• In late 2022, we began developing our newest product: PrecisePRP, a donor-derived off-the-shelf platelet-rich plasma for dogs and horses. We spent much of early 2023 finalizing the details of manufacturing, marketing, and all of the many pieces that come with developing a novel product such as this.
• In February, we attended our first of many veterinary conferences in Las Vegas, NV. Western Vet Conference is one of the largest shows in the industry and it was the first time we began previewing the upcoming PrecisePRP.
• In March, we announced a major expansion of our manufacturing and R&D facilities. We spent much of the year developing these facilities which are comprised of 13,765 square feet of class A biotech space. These facilities have been/will be used for internal VetStem projects, manufacturing for our sister company, Personalized Stem Cells, and for contract manufacturing of new veterinary biologics.
• In April, VetStem sponsored a dry lab at the annual IVAPM Pain Management Forum for the second year in a row. Veterinarians at this forum have a particular interest in multi-modal pain management and were excited to learn about the upcoming PrecisePRP.
• In July, VetStem CEO, Dr. Bob Harman, was featured on the Fuzzybutts and Friends podcast to discuss all things stem cell therapy for pets.
• In August, we announced the soft launch of PrecisePRP, which is currently still undergoing the FDA review process but is available at a discounted price in exchange for outcome data.
  

  PrecisePRP Canine and PrecisePRP Equine

• August also saw the VetStem Sales and Marketing team in Kansas City, MO for the annual Fetch DVM360 conference. We sponsored three of the Fetch shows this year and spoke about platelet-rich plasma options at each show.
• In September, VetStem sponsored a first of its kind stem cell workshop supporting wildlife conservation. The Stem Cell Technology for Genetic Rescue Workshop was held on September 17-20 in La Jolla, CA. Dr. Harman was among 45 global leaders in stem cell science, brought together to share their experience and expertise and to discuss how stem cell technology can further wildlife conservation efforts.
• Shortly after the workshop, Dr. Harman attended the annual North American Veterinary Regenerative Medicine Association (NAVRMA) conference in Kona, HI. This conference brings together some of the greatest minds in regenerative veterinary medicine.
• In early October, the Sales and Marketing team was back on the road. We did two shows back-to-back: Fetch Coastal in Atlantic City, NJ where we spoke about PRP and the American Association of Feline Practitioners (AAFP) conference in Memphis, TN where we sponsored two talks on feline medicine.
• In late November/early December, the Sales and Marketing team wrapped up a busy year of conferences at the annual American Associate of Equine Practitioners (AAEP) conference in San Diego, CA and the final Fetch DVM360 conference in Long Beach, CA. At both shows, Dr. Harman spoke about PRP and stem cell therapy.

So, there you have it. Another year in the books. It was an exciting year for us and, as always, we couldn’t do what we do without the support of our veterinary and pet owner clients. We hope that you and your loved ones have a wonderful holiday season, and we look forward to seeing what 2024 has in store for VetStem!

International Day of Veterinary Medicine is celebrated each year on December 9^th. This day was established to bring recognition to the tremendous efforts and impact of veterinary professionals around the world. Most pet owners appreciate the invaluable services veterinarians provide in keeping their pets happy and healthy, but there are additional reasons to recognize this group of dedicated, hard workers.

If you’ve been following along with our blog, then you’ve definitely heard the term “One Health.” In fact, we recently shared a blog recognizing One Health Day. One Health is the idea that veterinary and human health are inextricably linked. For instance, advances made in veterinary medicine have also helped in human healthcare. Examples include vaccines, organ transplants, numerous medications, and even stem cell therapy!

Another example of the link between human health and the health of animals is zoonotic diseases, or diseases that can be passed between animals and humans. There are numerous zoonotic diseases including rabies, intestinal parasites, and multiple viral, bacterial, and fungal infections. By controlling these diseases in animals, veterinary professionals are also helping to ensure a healthy human population.

So while we may appreciate our veterinarians for their tireless work to keep our pets feeling their best, International Day of Veterinary Medicine is a day to recognize the field as a whole. All veterinary professionals from vets to techs to scientists have a hand in keeping animals, and thereby people, healthy.

Today officially kicks off National Cat Lovers’ Month and we want to introduce you to the newest members of the VetStem Clowder! But first, if you’re curious about how VetStem Cell Therapy can be used in cats, check out our recent blog.

This sweet orange boy is Rusty. His favorite activities include causing trouble and stealing the dog’s bed. Additionally, he has a hankering for food that rivals a teenage boy. It’s been reported that he has already figured out how to open the pantry door. He’s also been known to jump on the dining room table and climb legs to access the food that should surely be shared with him. His mom is excited (or not…) to see how he reacts to the Christmas tree. Who wants to take bets on how that goes?

Our newest addition doesn’t have an official name yet, though he has earned a few nicknames including “Mako” (as in the shark…) or just simply, “Crazy.” He’s a rescue Siamese who was found in a box at just a week old. He was nursed back to health and is now lovingly described as “AWFUL but cute.” As you can see from his picture below, he loves to play with (read: torment) his dog sister, Darby. We know it’s not a great picture, but we feel it captures his personality perfectly. Darby wants to know if anyone would like a free Siamese kitten?

Happy National Take a Hike Day! As you have probably heard us say before, hiking can be a great exercise for both people and dogs to help control symptoms of osteoarthritis.

We frequently discuss the benefits of regular, low-impact exercise for dogs. Walking can be very beneficial when it comes to joint health. Low-impact exercise can lubricate joints and str

Mick, Dr. Harman’s dog, on a hike with a view!

engthen muscles, two benefits that may delay the onset or reduce the symptoms of osteoarthritis. Hiking can be a good way to mix up your regular walks around the neighborhood.

While hiking can be fun and beneficial for both dog and owner, it is best to check with your veterinarian before embarking on any major hikes. Experts agree that regular, short-interval exercise is key, as opposed to doing one big activity on the weekends, such as a long or strenuous hike. That being said, there are many hiking trails that are shorter and less strenuous. It’s a good idea to do your research to find a hike suited to your dog’s athletic ability.

Our very own founder and CEO, Dr. Bob Harman, spends his spare time hiking with his border collie, Mick. As an avid hiker, Dr. Harman sometimes spends several days hiking and camping in the mountains in and around California. With his experience and passion for the sport, Dr. Harman offers advice for hikers of all levels: Choose your trail and map out your hike before you leave the house. This will ensure you know what to expect on your hike so you can prepare yourself and your dog accordingly. Always make sure to pack enough water and a snack or two for both yourself and your canine companion. Keep an eye out for signs of fatigue, dehydration, or discomfort in your dog. If you notice any concerning signs, it may be best to turn back before finishing the hike. You can always try again another day!

Happy trails, my friends!

As you may know, VetStem has worked with multiple exotic animal organizations to provide stem cell therapy to several exotic species including elephants, bears, numerous aquatic animals, and big cats, just to name a few. These animals have been treated for everything from orthopedic conditions to viral diseases to organ failure to traumatic injuries and more. Given our great deal of experience, it’s no wonder that VetStem CEO, Dr. Bob Harman, was recently invited to participate in the first of its kind stem cell workshop supporting wildlife conservation.

The Stem Cell Technology for Genetic Rescue Workshop was held on September 17-20, 2023, in La Jolla, California. The workshop brought together 45 global leaders in stem cell science to share their experience and expertise and to discuss how stem cell technology can further wildlife conservation efforts. Not only did Dr. Harman bring real life experiences to the discussion, VetStem was also a sponsor of the workshop.

At VetStem, we take our job very seriously when it comes to the research and development of innovative regenerative medicine treatments for animals and diseases that have minimal treatment options. Maintaining the health and well-being of endangered exotic animals is particularly crucial and has become a community effort.

While our primary goal is to bring relief to the animals that need it, there is potential that stored stem cells may aid in wildlife conservation efforts down the line. VetStem has the ability to cryopreserve stem cells and currently has a bank of stem cells from over 40 different exotic animal species. We are happy to contribute to the mission and will continue our own research to develop potentially life-saving stem cell treatments for these animals.

Today, November 3^rd, is One Health Day. According to the One Health Commission, “One Health Day answers the urgent need for a One Health trans-disciplinary approach towards solving today’s critical global health challenges.” At VetStem, we have seen this idea of “one health” in action with the creation of our human company, Personalized Stem Cells, Inc.

Personalized Stem Cells (PSC) was formed in 2018 to bring legitimate stem cell therapies to people. PSC used all of VetStem’s animal data to receive approval for two FDA approved stem cell clinical trials. The first clinical trial was for knee osteoarthritis in people, a condition that numerous dogs have received VetStem Cell Therapy for. The second clinical trial utilized VetStem’s intravenous injection data to receive approval to treat COVID-19 patients. Both clinical trials demonstrated solid safety and preliminary efficacy.

Moving forward, PSC plans to pursue an additional clinical trial for knee osteoarthritis, a traumatic brain injury (TBI) trial, and more! Additionally, PSC has the ability to bank stem cells for potential future use, much like VetStem’s StemInsure program. There are a few different programs through the FDA that may allow patients to access their stem cells.

But One Health has worked both ways for us. Interestingly enough, the success of the COVID-19 trial gave us the idea to use stem cells in the treatment of Elephant Endotheliotropic Herpesvirus (EEHV). EEHV is a lethal viral infection that can cause a highly fatal hemorrhagic disease in elephants. VetStem has provided stem cell doses to several zoos in the United States who had elephants with EEHV and has gathered some promising data.

All of that is to say that at VetStem, we know a thing or two about One Health and we’re happy to bring awareness to this cause.  

National Cat Day is fast approaching, and we never miss an opportunity to talk about VetStem Cell Therapy for cats. While stem cells are primarily used for orthopedic conditions, many veterinarians have used VetStem Cell Therapy to help treat and control symptoms associated with diseases such as kidney disease, gingivostomatitis, and inflammatory bowel disease.
All three of these diseases are prevalent in cats and have limited treatment options.

Stem Cells for Kidney Disease

Kidney disease is one of the most common causes of sickness and death in cats. Common symptoms can include weight loss, lethargy, variable appetite, and poor coat quality. Some cats may also drink and urinate more, vomit, or have diarrhea.Unfortunately, treatment options for cats with kidney disease are limited and can be costly.

The good news is, based upon our own data as well as the data of others, we believe that stem cells may help improve the symptoms and quality of life in some cats with kidney disease. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment. Owners and veterinarians have also reported improved appetites, weight gain, and increased energy in cats treated with VetStem Cell Therapy.

Stem Cells for Gingivostomatitis

Gingivostomatitis is another debilitating condition found in cats. It is characterized by chronic inflammation of the gums, which can lead to inappetence, reduce grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, and pain medications and/or full mouth teeth extractions.

A recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. Additionally, veterinarians and cat owners have reported an improvement in symptoms and quality of life in cats treated with VetStem Cell Therapy.

Stem Cells for Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is an intestinal disorder that affects both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Multiple cats have received VetStem Cell Therapy for IBD (dogs too!). And we have had reports from veterinarians and owners regarding the improvement of their patients and pets after treatment with stem cells. Additionally, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

If you think your cat may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

We spent the better part of last week attending two different veterinary conferences. We love attending these shows as they are a great way to meet with existing and potential clients to talk all things regenerative veterinary medicine. They allow us the opportunity to speak to and educate veterinarians and veterinary technicians from all over the country about VetStem Cell Therapy and how they can implement this therapeutic modality in their practice.

The first part of the week was spent in Atlantic City for the Fetch Coastal veterinary conference. This is a smaller group consisting primarily of small animal veterinarians. Many showed interest in regenerative medicine and our platelet-rich plasma options. Fetch hosts multiple shows throughout the U.S. We attended Fetch DVM360 in Kansas City in August and will attend Fetch Long Beach later this year.

Over the weekend, the team was in Memphis for the annual American Association of Feline Practitioners conference. AAFP is a great show with tons of enthusiastic cat vets. Many veterinarians at this conference show interest in our clinical research programs, such as inflammatory bowel disease, gingivostomatitis, and renal disease, as these conditions tend to be prevalent in cats and have limited treatment options.

If you missed us at these shows, don’t worry! Show season is not over yet! You can find VetStem at the American Association of Equine Practitioners (AAEP) conference and Fetch Long Beach in late November/Early December. And we will of course be back in Las Vegas in February for the Western Veterinary Conference.