As you probably noticed, our primary focus in this blog tends to be arthritis.  We occasionally discuss torn cruciate ligaments and also have a few blogs about various disease processes that may be helped with stem cells.  One thing we have not spent much time on is stem cell therapy for muscle injuries.

Muscle injuries are not uncommon in the athletic dog.  Typical therapies for muscle injuries include rest, nonsteroidal anti-inflammatory drugs, and physical rehab.  Unfortunately, these therapies generally do not prevent the formation of fibrosis (scar tissue) or muscle contracture which ultimately leads to functional impairment.

In a study done on two police dogs (both German Shepherds) with injuries to their semitendinosus muscle, both dogs returned to the line of duty with a normal gait and no signs of lameness after receiving VetStem Regenerative Cell Therapy.  This study was, in fact, the first report of using stem cells to treat skeletal muscle injuries in dogs.

If your dog has injured a muscle, speak to your veterinarian about whether VetStem Cell Therapy may help.  Or you can contact us for a list of VetStem providers in your area.

Anthony, a competitive hunter-jumper, faced a real challenge when he tore his right meniscus in 2014.  Luckily, Anthony’s mom Lisa contacted experienced stem cell provider, Dr. Ruth-Anne Richter of Brandon Equine Medical Center.  Anthony received VetStem Regenerative Cell Therapy in January 2014 and again in June 2014.

After taking some time off to recuperate, Anthony began competing again.  Between 2016 and 2017, Anthony took a few reserve championships.  But earlier this year, in March 2018, Anthony won grand champion in the Adult Maiden Division at HITS VIII Ocala Winter Finals.  This was a dream come true for Lisa.

You can read more details about Anthony’s stem cell treatment here.

If your horse has suffered an injury, stem cell therapy may help to get him/her back under the saddle.  VetStem Regenerative Cell Therapy has been used in horses since 2004 and has been shown to help relieve potentially career ending injuries such as in Woody’s case and Zan’s case.  Speak to your veterinarian today or contact us to receive a list of VetStem providers in your area.

Jack is a Great Pyrenees.  As the name of the breed suggests, he is a great big boy.  Unfortunately, large breed dogs tend to develop orthopedic issues such as arthritis as they age.  Unfortunately, Jack was diagnosed with hip dysplasia at a very young age.  He wasn’t even a year old when he began showing symptoms of arthritis. 

His mom, Rebecca, acted swiftly and visited veterinary surgeon Dr. Andrea Hayes of Boone Animal Hospital.  Dr. Hayes gave Rebecca a few options including total hip replacement and treatment with VetStem Regenerative Cell Therapy.  After much deliberation, Rebecca selected the least invasive option: stem cell therapy.

Jack received his first round of injections in 2014 and improved greatly!  Approximately four years later, Jack received a second round of stem cell injections and again had a great response.  You can read more details about Jack’s stem cell treatment and results here.

Unfortunately, Jack’s story is not uncommon.  Large breed dogs tend to develop orthopedic issues such as arthritis as they age, that is, if they’re lucky enough to not be born with a condition such as hip dysplasia that can lead to arthritis while they are still young.  Fortunately, stem cell therapy may help to relieve symptoms of arthritis and can potentially help dog’s avoid invasive and costly major surgeries.  Keep in mind, StemInsure is a great option for large breed puppies that will likely develop arthritis down the road.

In addition to stem cell processing services, VetStem distributes platelet therapy kits to small and large animal veterinarians across the United States and Canada.  Platelet therapy is similar to stem cell therapy in that the patient’s own cells are collected, concentrated, and then reinjected into the affected area.  Unlike stem cell therapy, platelet therapy requires a blood collection and the process of concentrating the healing cells is performed by your veterinarian in the clinic.

How does platelet therapy work?  The scientific answer is that platelets activate by exposure to damaged tissue, releasing their granular contents which include anabolic growth factors.  These growth factors help attract progenitor cells to the injury site and play a key role in stimulating tissue repair through fibroblast expansion and cellular matrix production.  In other, less technical terms, when the concentrated platelets are injected into the site of damaged tissue, the platelets signal additional healing cells to migrate to the affected area to begin the process of tissue repair.

The great thing about platelet therapy is it can be performed in conjunction with stem cell therapy to further aid the healing process.  In our opinion, stem cell and platelet therapies are very different regenerative medicine solutions that can work synergistically. They each have their place and can benefit patients in different circumstances. We see the combination of adipose stem cell therapy and platelet therapy as the “platinum standard” for regenerative medicine.  While the idea of stem cell therapy is to deliver as many regenerative cells to the affected area as possible, by adding platelet therapy on top of it, additional healing cells will migrate to the area to further stimulate local tissue repair processes.  And like stem cell therapy, platelet therapy is autologous, meaning the animal is both the donor and the recipient.  Thus, there is minimal risk of rejection and reaction when performed under sterile conditions.

Our primary platelet therapy product for small animals is Pall Veterinary Platelet Enhancement Therapy or V-PET™.  We’ve seen much success with V-PET™ such as in Pippa Rose’s case and Pearl’s case.  But, similar to stem cell therapy, every patient’s response will vary.  Your veterinarian can best determine if your dog may benefit from platelet therapy.

If you have questions or would like VetStem to help you locate a platelet therapy provider near you, please contact us.  To read more about platelet therapy and success stories, click here and here.

Stuart is a fun-loving Labrador that, like most Labs, loves to play fetch.  In 2017, when Stuart began showing signs of an injury, his owner, Cynthia, took him to her veterinarian, Dr. Cindy Echevarria at VCA University Animal Hospital in Dallas.  After an unsuccessful trial of a multitude of injectable and oral medications, Dr. Echevarria recommended treatment with VetStem Regenerative Cell Therapy.

In July 2017, Stuart had his right carpus (wrist) and shoulder injected, as well as an intravenous injection of his own stem cells.  Approximately one week after the procedure, Stuart was feeling better and Cynthia commented that he was almost a completely different dog.

You can read the rest of Stuart’s story here.

We recently checked in on Stu and Cynthia reported that he is as happy and active as ever!  She stated, “Stem cell treatment was a lifesaver!”

If your dog has been diagnosed with a soft tissue injury, stem cell therapy may help him/her get back in the game.  Be sure to speak to your veterinarian or contact us to receive a list of VetStem Credentialed veterinarians in your area. 

Similar to storing your baby’s stem cells at birth, the canine StemInsure provides peace of mind with banked stem cells that can be used later in life should your dog require them.  While we can’t bank cord blood/tissue like we do with infants, the StemInsure is similar to our standard stem cell process where we extract stem cells out of a small amount of fat from your furry friend.

The great thing about the canine StemInsure is the fat can be collected in conjunction with an already scheduled, routine procedure such as a spay or neuter.  When your vet is performing the procedure, they would collect a very small amount of fat from your dog and send it to our laboratory to be processed where the small number of stem cells would be extracted and cryopreserved.  This process costs considerably less since it is a smaller amount of fat than is required for our normal process. If your dog develops arthritis or injures a tendon or ligament down the road, those cells would be available without requiring an additional anesthetic procedure to collect more fat tissue.  For this reason, we recommend StemInsure for all large breed puppies and other “at risk” breeds that tend to develop orthopedic issues as they age.

StemInsure is not only appropriate for puppies, however.  Dogs of all ages and breeds can benefit from this procedure.  An example would be an older dog that is undergoing an anesthetic procedure such as a dental cleaning.  Older animals tend to be a higher anesthetic risk than puppies so it is ideal to minimize their time under anesthesia.  Rather than removing a larger amount of fat from your dog’s abdomen, your vet can quickly remove a small amount of fat from beneath their skin in an effort to reduce the amount of time spent under anesthesia.

Unlike our standard stem cell process where your vet sends us fat and we send back injectable stem cell doses 48 hours later, the StemInsure sample cannot be used for immediate treatment.  Instead, the smaller tissue sample size yields enough cells that can be used to culture, or grow, a lifetime supply of stem cell doses for treatment at an additional cost when you need them.  This culture takes about 3-4 weeks however so if your dog requires treatment sooner than that, discuss with your veterinary stem cell provider which option will be best for your dog.

To find a veterinary stem cell provider in your area, click here.

Remember our friend, Argo, the chocolate Labrador that was featured on the local news for his treatment with VetStem Regenerative Cell Therapy?  He just had his second cameo on a longer news segment that discussed his stem cell and platelet therapy treatments for arthritis.  You can watch the new video and read his story here.

Both Dr. Angie Zinkus and Dr. Kathy Mitchener have been credentialed to perform VetStem Regenerative Cell Therapy for over a decade.

One thing we would like to point out: the article states that Argo’s platelet therapy required a 48-hour processing period.  While this is true of stem cell therapy, platelet therapy is an in-clinic procedure that can be done in a matter of a few hours.  VetStem is the distributor of the Veterinary Platelet Enhancement Therapy kit (V-PET™) but your veterinarian will perform the blood collection, processing, and injection.  For more information on Veterinary Platelet Enhancement Therapy, click here.  Or you can read V-PET™ success stories here and here.

If you think your pet may benefit from VetStem Regenerative Cell Therapy, speak to your veterinarian today.  Or you can contact us to receive a list of VetStem Credentialed veterinarians in your area.

In our last two blog posts, we discussed stem cells for cats.  In addition to arthritis, stem cells may be beneficial for felines with Chronic Kidney Disease (CKD) and Inflammatory Bowel Disease (IBD).  In this week’s blog, we will discuss feline Gingivostomatitis.

Gingivostomatitis is a disease affecting the mouth of felines.  It causes oral pain which leads to other symptoms such as decreased appetite, reduced grooming, and weight loss.  The most common treatment is extracting all the cat’s teeth, however only about 70% of cats will respond to this treatment.  Those cats that do not respond will require lifelong treatment with medications.

Two small studies on cats that had full mouth extractions conducted at the University of California Davis have shown that fat-derived stem cell therapy led to improvement or remission in the majority of cats treated.  VetStem believes that fat-derived stem cells without full extractions may be beneficial.  While a few veterinarians have seen favorable results using VetStem cell therapy, more investigation is needed.

If your cat has Chronic Kidney Disease, Inflammatory Bowel Disease, or Gingivostomatitis, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.

This concludes our “Stem Cell Therapy for Cats” blog series.  Thanks for reading!  If you have any questions, feel free to contact us at info@vetstem.com.

Last week, we shared part 1 of this blog series regarding stem cells for cats.  While stem cells may be an effective treatment for arthritic felines, there are a few other diseases for which stem cells may be beneficial including Chronic Kidney Disease, Inflammatory Bowel Disease, and Gingivostomatitis.  In last week’s blog, we discussed Chronic Kidney Disease.  In part 2 of this series, we will look at Inflammatory Bowel Disease and how stem cells may be of benefit.

Inflammatory Bowel Disease (IBD) is a chronic gastrointestinal disorder characterized by inflammation in the gut.  Some of the common symptoms include diarrhea, vomiting, reduced appetite, and weight loss.  It is important to note however that these symptoms can be indicative of several various ailments such as food allergies, bacterial or viral infections, and intestinal parasites.  Typically, these problems can be resolved with dietary changes and/or antibiotics while IBD is generally responsive to immunosuppressive therapy such as steroids.

Also, when considering stem cell treatment for cats with IBD, it is necessary to rule out Lymphoma as the underlying cause of the symptoms.  VetStem Regenerative Cell Therapy is contraindicated in patients with active cancer.

In a case study where a 4-year-old Himalayan cat developed IBD, treatment with VetStem Regenerative Cell Therapy quickly resolved the cat’s diarrhea and vomiting and led to an increased appetite.  To add to that, in a recently published paper, 5 out of 7 cats that were treated with stem cells were significantly improved or had complete resolution of symptoms whereas the 4 control cats had no improvement.¹

If your cat has Inflammatory Bowel Disease, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.  And stay tuned for part 3 of this blog series in which we will discuss stem cells for Gingivostomatitis.

Note: Dogs with IBD may benefit from stem cell therapy as well.

1. Webb, TL and Webb, CB (2015) Stem cell therapy in cats with chronic enteropathy: a proof-of-concept study. J Fel Medand Surg(10). 17, 901-908.

A few weeks ago, we shared a blog post about stem cell therapy for arthritic cats.  Similar to stem cell therapy for dogs, there are additional common feline diseases for which stem cells may be beneficial.  These diseases include Chronic Kidney Disease (CKD), Inflammatory Bowel Disease (IBD), and Gingivostomatitis. VetStem is still evaluating the use of stem cells for these disease processes with some favorable results being seen.  In part one of this blog series, we will discuss feline Chronic Kidney Disease and how VetStem Regenerative Cell Therapy may provide some relief.

Chronic Kidney Disease is a major cause of morbidity and mortality in cats.  Common symptoms include lethargy, increased urine output, and weight loss.  Other than a kidney transplant, which is costly and invasive, there really is no definitive cure for CKD.  Current therapies include supportive measures such as subcutaneous fluids and special diets.  The disease process, however, will continue to progress.

VetStem veterinarians have seen some promising results in the treatment of feline CKD.  Based upon data from a small number of feline patients treated with VetStem Regenerative Cell Therapy, blood kidney values were slightly to moderately improved after treatment.  While more evaluation is necessary, these preliminary results suggest that stem cell therapy may be a low-risk treatment option for cats with CKD.

If your cat has Chronic Kidney Disease, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.  And stay tuned for part 2 of this blog series in which we will discuss stem cells for Inflammatory Bowel Disease.