Archive for the ‘Gingivostomatitis’ Category

Dec 3, 2021

VetStem Cell Therapy for Cats

It’s that time of year again: National Cat Lovers’ Month! And as always, we’re going to take this opportunity to tell you all about VetStem Cell Therapy for cats. While dogs and horses are most commonly treated for orthopedic conditions such as osteoarthritis or injured tendons and ligaments, cats more often than not receive VetStem Cell Therapy for other diseases.

Feline Renal Disease

Nearly 200 cats have received VetStem Cell Therapy for kidney disease. A common disease in cats, chronic kidney disease (CKD) is a frequent cause of sickness and death in cats. In fact, some reviews suggest that CKD may be the number one cause of sickness and death in older cats. Unfortunately, treatment options are limited and can be costly.

Based upon data from the numerous cats treated with VetStem Cell Therapy, we believe that stem cells may help improve the symptoms and quality of life in some cats with CKD. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment. More data is necessary however and we continue to research stem cell therapy for this disease as part of our clinical research department.

Gingivostomatitis

Another potentially debilitating condition is gingivostomatitis. This disease is characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduce grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, and pain medications and/or full mouth teeth extractions.

Current literature supports the notion that gingivostomatitis is an autoimmune disease. Mesenchymal stem cells have demonstrated the ability to migrate to areas of inflammation, down-regulate inflammation, modulate the immune system, and repair damaged tissue. Additionally, a recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. While more research is needed, preliminary results suggest that VetStem Cell Therapy can improve the symptoms of some cats with gingivostomatitis.

Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is a gastrointestinal disease that can affect both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Multiple cats have received VetStem Cell Therapy for IBD (dogs too!). And we have had reports from veterinarians and owners regarding the improvement of their patients and pets after treatment with stem cells. As stated above, stem cells migrate to areas of inflammation, down-regulate inflammation, modulate the immune system, and repair damaged tissue, all of which can contribute to healing inflamed and diseased intestines. Additionally, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

Orthopedic Conditions

Let’s not forget that cats can get arthritis too! Osteoarthritis (OA) in cats is a lot more common than you may think. It is estimated that 45% of all cats and 90% of cats over age 10 are affected by arthritis in some way. Unfortunately, cats can be masters at hiding their pain and thus, feline arthritis tends to go undiagnosed.

Though most of our osteoarthritis data is from dogs, cats have experienced similar results when treated with VetStem Cell Therapy. Stem cells may reduce pain and inflammation associated with osteoarthritis and may lead to the regeneration of damaged joint tissues. This can result in increased mobility and a better quality of life for your kitty.

So, there you have it: VetStem Cell Therapy for cats in a nutshell. It’s important to remember that kidney disease, gingivostomatitis, and inflammatory bowel disease are still in the investigational stages. And as with any medical treatment, not all cats will respond positively. That being said, if you think your cat may benefit from VetStem Cell Therapy, contact us to receive a list of VetStem providers in your area.

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Aug 6, 2021

VetStem Cell Therapy for Diseases in Cats

This coming Sunday, August 8th, is International Cat Day! We thought this would be the perfect opportunity to discuss the use of stem cells for various diseases in cats. Like dogs and horses, VetStem Cell Therapy can be used in cats to treat orthopedic conditions such as osteoarthritis and injured tendons and ligaments. But there are several other diseases for which VetStem Cell Therapy may be helpful.

Chronic Kidney Disease

A common disease in cats is kidney disease. Chronic Kidney Disease (CKD) is a common cause of sickness and death in cats. In fact, some reviews suggest that CKD may be the number one cause of sickness and death in older cats. Unfortunately, treatment options are limited and can be costly.

One potential treatment option is VetStem Cell Therapy. Nearly 200 cats have received VetStem Cell Therapy for CKD and veterinarians have seen some promising results. Based upon data from a small number of feline patients treated with VetStem Cell Therapy, blood kidney values were slightly to moderately improved after treatment. While more evaluation is necessary, these results suggest VetStem Cell Therapy may be a viable treatment option for cats with CKD.

Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is a gastrointestinal disease that can affect both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Several cats have received VetStem Cell Therapy for IBD. In fact, one of our veterinary clients, Dr. Joel Stone, wrote a guest blog about one of his feline patients who experienced relief from IBD after treatment with VetStem Cell Therapy. In one of our own case studies, a 4-year-old Himalayan cat developed IBD and treatment with VetStem Cell Therapy quickly resolved the cat’s diarrhea and vomiting and led to an increased appetite with no recurrence. To add to that, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells were significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

Gingivostomatitis

Another unfortunate disease that affects cats is gingivostomatitis. Gingivostomatitis affects the mouths of felines and causes oral pain which leads to other symptoms such as decreased appetite, reduced grooming, and weight loss. The most common treatment is extracting all the cat’s chewing teeth, however only about 70% of cats will respond to this treatment. The remaining 30% of cats that do not respond will require lifelong treatment with medications.

Fewer cats have received VetStem Cell Therapy for gingivostomatitis than CKD, however veterinarians have seen favorable results none the less. In addition to our own data, two small studies conducted at the University of California Davis showed that when fat-derived stem cell therapy was utilized in addition to teeth extractions, there was improvement or remission in the majority of cats treated. VetStem believes that fat-derived stem cell therapy without full extractions may be beneficial.

As you can see, VetStem Cell Therapy may be useful for a number of disease processes. Though the above conditions are still in the investigative stages, the preliminary results look very promising! If you think your cat may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us for a list of VetStem providers near you.

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