As we wrap up our Animal Pain Awareness Month blog series, we’re revisiting the important role that VetStem Cell Therapy can play in managing pain. In last week’s post, we discussed how stem cells help reduce both acute and chronic pain. This week, we’ll show how that science translates into real-world results by sharing the story of Nellie-Jane, a beagle who was struggling with arthritis in multiple joints.

In addition to hip dysplasia, which caused painful hip arthritis, Nellie was also diagnosed with moderate arthritis in her elbows, knees, and shoulder. These degenerative conditions can severely limit mobility and quality of life, often leaving dogs uncomfortable despite standard therapies. To help Nellie, her veterinarian, Dr. Keith Clement of Burnt Hills Veterinary Hospital, recommended VetStem Cell Therapy.

To begin her treatment, Dr. Clement collected a small sample of fat tissue from Nellie’s abdomen, which was sent to the VetStem laboratory for processing. Technicians extracted and concentrated her stem and regenerative cells, preparing eight doses for use. Within 48 hours, Nellie received stem cell injections into each of her arthritic joints, as well as an intravenous injection.

According to her owner, the results were clear: “Stem cell therapy made a huge difference for Nellie. It gave her back a lot of mobility and reduced her pain.” Nellie’s case is a great example of how stem cells don’t just support healing, they directly reduce pain, target inflammation, and support tissue repair. By addressing pain at its source, VetStem Cell Therapy helps pets regain comfort, stay active, and enjoy a better quality of life.

Curious if your pet may benefit from VetStem Cell Therapy? Speak to your veterinarian or contact us to receive a list of VetStem providers near you.

Nellie-Jane

In this third installment of our Animal Pain Awareness Month blog series, we’re focusing on how VetStem Cell Therapy can help manage pain in pets. We know how challenging it is to watch a beloved animal struggle with discomfort, whether from arthritis, an injury, or post-surgical recovery. What makes VetStem Cell Therapy unique is that it not only supports the repair of damaged tissue but also works directly to reduce both acute and chronic pain through multiple mechanisms of action.

One of the primary ways stem cells help manage pain is by reducing inflammation, which is often a key contributor to both acute and chronic pain. After administration, stem cells migrate to areas of injury or disease and release bioactive molecules that decrease inflammation and modulate the immune response, leading to improved comfort and mobility for pets. In addition to controlling inflammation, stem cells stimulate the repair and regeneration of damaged tissues such as cartilage, tendons, and ligaments. As these structures heal, the underlying source of pain is reduced, leading to improved long-term outcomes for pets.

More recent literature indicates that stem cells can also target both acute and chronic pain directly. Initially, stem cell therapy was mainly associated with healing, regeneration, and inflammation reduction. However, newer studies have explored how stem cells can directly influence pain perception. These studies reveal that stem cells release cytokines—small proteins that can act similarly to opioids in blocking pain. Interestingly, these pain-relieving effects can be reversed by Naloxone, an opioid antagonist.

As research continues to advance our understanding of pain and regenerative medicine, VetStem Cell Therapy remains a trusted option for veterinarians and pet owners alike. By addressing inflammation, promoting tissue repair, and directly modulating pain signals, stem cell therapy provides a natural, targeted approach to help pets regain comfort, mobility, and quality of life. For pets dealing with arthritis, orthopedic injuries, or post-surgical discomfort, VetStem Cell Therapy offers a pathway to both relief and long-term healing.

If you think your pet may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

As we continue Animal Pain Awareness Month, we want to highlight an important topic: recognizing the signs of pain in dogs and cats. Both species, but especially cats, are skilled at hiding discomfort. While some signs of pain are obvious, others can be subtle, yet all may indicate that a trip to the veterinarian is needed. Identifying and addressing pain early is essential to maintaining your pet’s quality of life.

Before diving into the signs, it’s helpful to understand the difference between acute pain and chronic pain.

• Acute pain comes on suddenly and is usually short-term. It often results from an injury, illness, or surgical procedure.
• Chronic pain is more subtle and develops gradually over time. A common example is the ongoing discomfort caused by osteoarthritis.

While acute pain is typically easier to recognize, chronic pain can be much harder to detect. To help pet parents better identify when their pets may be in pain, the International Veterinary Academy of Pain Management (IVAPM) has compiled a list of the most common signs. This resource is especially valuable for those who may not realize their pet is suffering.

Common signs of pain in pets include:

• Decreased activity such as unwillingness to accompany on walks or play, difficulty going up or down stairs, reluctance to jump onto as higher surfaces as normal (cats), slow to stand after laying down.
• Changes in their mood, personality and everyday behavior, such as being more anxious or fearful, becoming antisocial and distant, being grumpy and intolerant to other animals and people.
• Decreased appetite and interest in food.
• Over grooming or licking a particular areas on their body or in the environment.

IVAPM has also provided checklists for both dogs and cats that may help to determine if your pet is experiencing pain.

Being able to recognize when your pet is in pain is an important part of keeping them happy and healthy. Even subtle changes in activity, behavior, or appetite may be a sign that something isn’t right. Resources like IVAPM’s pain checklists can help pet parents spot these signs early and know when it’s time to seek veterinary care. By catching pain sooner rather than later, you can help ensure your dog or cat enjoys the best possible quality of life.

September is Animal Pain Awareness Month, an initiative spearheaded by the International Veterinary Academy of Pain Management (IVAPM). This annual event is dedicated to raising awareness about pain in animals and the importance of proper pain management in veterinary medicine. At VetStem, we share this mission and recognize the vital role that IVAPM plays in advancing education, research, and treatment strategies for managing animal pain.

Animals, like people, experience both acute and chronic pain. Whether from surgery, injury, or conditions such as arthritis, untreated pain can have profound effects on an animal’s health, mobility, and overall quality of life. There are many signs that a pet may be in pain, which we will cover in next week’s blog.

At VetStem, we also recognize the tremendous impact that organizations like IVAPM have on advancing veterinary care. Our mission – to improve the lives of animals through regenerative medicine – aligns closely with IVAPM’s focus on reducing pain and enhancing quality of life. VetStem Cell Therapy has helped numerous dogs, cats, and horses with painful orthopedic conditions experience significant improvements in mobility and comfort. We believe that regenerative medicine is a valuable addition to the multimodal pain management approach.

Animal Pain Awareness Month also serves as an important reminder for pet owners to stay alert to subtle signs of discomfort in their pets. Limping, changes in activity, decreased appetite, or altered behavior can all be indicators of pain. If you suspect your pet may be in pain, consult your veterinarian to discuss diagnosis and treatment options.