Archive for the ‘VetStem Cell Therapy’ Category

Jun 10, 2022

VetStem Cell Therapy Helps Cat with Gingivostomatitis

We’ve talked about treating feline gingivostomatitis with VetStem Cell Therapy a few times on this blog. But sometimes we need more than just the science to describe how this treatment can potentially help cats. So this time, we will share a success story. Finn is a Siamese cat with gingivostomatitis who experienced an improvement in his symptoms after treatment with VetStem Cell Therapy.

Gingivostomatitis Symptoms

At just five months old, Finn was diagnosed with gingivostomatitis. Gingivostomatitis is a debilitating condition characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduced grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, pain medications, and/or full mouth teeth extractions.

VetStem Cell Therapy for Gingivostomatitis

Current literature supports the notion that gingivostomatitis is an autoimmune disease. Mesenchymal stem cells have demonstrated the ability to migrate to areas of inflammation, down-regulate inflammation, modulate the immune system, stimulate neoangiogenesis (formation of new blood vessels), and repair damaged tissue. Additionally, a recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. While more research is needed, preliminary results suggest that VetStem Cell Therapy can improve the symptoms of some cats with gingivostomatitis.

Finn’s Treatment with VetStem Cell Therapy

Finn

Finn’s owners tried several medications in an effort to improve his symptoms, but nothing worked. They were determined to not have all of his teeth extracted and were willing to do whatever it took. His veterinarian recommended treatment with VetStem Cell Therapy and just shy of his first birthday, Finn received stem cell therapy.

To begin the process, fat was collected from Finn’s abdomen during a minimally invasive anesthetic procedure. The fat was sent to the VetStem processing laboratory. Lab technicians processed his fat to extract and concentrate his stem and regenerative cells and Finn received one intravenous injection of his own cells. Approximately four weeks later, Finn received a second intravenous dose using some of the stem cells banked from his initial fat collection.

According to his owners, Finn responded well to the treatment. His owner stated, “[the stem cell treatment] seemed to improve and maintain his condition especially over time so that Finn is happy, healthy, and living a great life. We plan to administer cells every year or so to keep his condition manageable and hopefully keep him healthier too.”

If your cat has gingivostomatitis, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy. Or contact us to receive a list of VetStem providers in your area.

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Jun 3, 2022

VetStem Cell Therapy for Canine Allergies

As some of you know all too well, many dogs suffer from “allergies,” otherwise known as Canine Atopic Dermatitis (CAD). CAD is a genetic disease that predisposes a dog to certain allergen sensitivities. The allergen(s) are environmental such as pollens, molds, dust mites, dander from other animals, or normal skin organisms.

What is Canine Atopic Dermatitis?

While there is still much to learn about CAD disease, we have learned that atopic dermatitis occurs due to a skin barrier defect, which allows allergens to absorb deeper into the skin where the immune system can access them. Thus, when an atopic dog comes into contact with the offending allergen(s), their body creates a skewed immune response leading to an allergic reaction.

Traditional Treatments for Canine Atopic Dermatitis

Though there are numerous potential treatment options for CAD, most of them are geared toward controlling the dog’s itchiness and do not cure the condition. Some of the more conventional treatment options include frequent bathing with specially formulated shampoos, as well as oral and injectable medications. CAD is a lifelong disease that requires lifelong management and unfortunately, treatment can be time consuming and expensive.

VetStem Cell Therapy for Canine Atopic Dermatitis

Multiple veterinarians have utilized VetStem Cell Therapy to treat atopy in both dogs and cats. While the research is limited in this disease, there is some promising anecdotal evidence. Some veterinarians have reported an improvement in symptoms after treatment with stem cells. In some cases, patients have required less allergy medication than before stem cell therapy.

That being said, some patients have not experienced improvement in symptoms. So, while we can’t say that stem cells will help every dog with atopic dermatitis, we do believe that some may benefit from treatment with VetStem Cell Therapy based on the responses reported from the veterinarians and owners who have implemented it. As with most medical treatment options, each patient will respond differently so results cannot be guaranteed.

If you think your allergic pet may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to find a VetStem provider near you.

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May 13, 2022

VetStem Cell Therapy Helps Senior Lab Walk Again

We absolutely love hearing stem cell success stories from pet owners. But some stories are extra touching because it’s clear that VetStem really improved a pet’s quality of life. That’s the case with Molly, a senior chocolate lab who was suffering from severe osteoarthritis and a potential spinal condition.

Molly

Osteoarthritis and Neurological Issue?

Molly has severe osteoarthritis (OA) in her hocks (ankles) and her left elbow. With a noticeable limp in her left front leg, one veterinarian called her elbow a mess after seeing X-rays of the joint. But Molly’s condition quickly deteriorated when one day she suddenly couldn’t walk at all. According to her owners, she was unable to bear any weight on her back legs and her back paws knuckled under when her owners tried to help her stand.

Her veterinarian worried that Molly may have a neurological issue such as a herniated disc in her spine, which can sometimes lead to being unable to walk. An MRI was offered however Molly’s owners elected to use the money to have Molly treated with VetStem Cell Therapy instead.

Treatment with VetStem Cell Therapy

Molly’s veterinarian, Dr. Rebecca Wolf of Metropolitan Veterinary Associates, collected fat tissue from Molly’s abdomen during a minimally invasive anesthetic procedure. The fat was aseptically packaged and shipped to the VetStem laboratory in Poway, California where VetStem lab technicians processed the fat to extract and concentrate the stem and regenerative cells contained therein. Molly’s cells were divided into doses and four stem cell injections were shipped to Dr. Wolf for treatment. Approximately 48 hours after the initial fat collection procedure, Molly received one stem cell injection into each hock, her left elbow, and intravenously.

Molly Regains Her Ability to Walk!

According to her owner, Molly had a great response to the stem cell therapy. Just two weeks after her injections, Molly was able to support her own weight with assistance. At her one month recheck appointment, Molly was able to take a few steps. And just shy of two months post-stem cell therapy, Molly was walking on her own again. When her back paws were flipped over, she righted them within two seconds.

Molly’s owner stated, “She is walking again on her own and without assistance, and she is definitely limping less on that front elbow. While we do realize at her age and the severity of arthritis in her joints that she won’t be a puppy again, I would definitely expect her to continue to improve and continue to be mobile. I would do this again for her in a heartbeat, and we are so thankful this technology exists. Thank you, VetStem, for giving us back our happy girl.”

Osteoarthritis is one of the most common diseases in dogs and pain associated with osteoarthritis can greatly reduce a dog’s quality of life. If you think your dog may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to find a VetStem provider near you.

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Mar 11, 2022

VetStem Cell Therapy in Dog with Inflammatory Bowel Disease

It happens occasionally that a pet is treated with VetStem Cell Therapy for one condition, such as osteoarthritis, but the owners notice that a separate condition improves as a result of the therapy. That was the case with Finn, a German Shepherd who is owned by Dr. Lesley Gonzales of Gruda Veterinary Hospital.

Finn was adopted as an adult after he was found in the desert of Yuma, AZ. Thus, nothing was known about his previous medical history. From the get-go, he experienced gastrointestinal issues including chronic diarrhea, intermittent vomiting, and difficulty gaining and maintaining weight. After multiple tests ruled out infectious diseases, his veterinarian mom put him on a strict limited-ingredient diet, which helped to somewhat improve his symptoms but not entirely.

Finn

Then, in 2020, Finn partially tore his cruciate ligament. Due to his gastrointestinal issues, Finn was extremely limited on what medication he could take to help control his inflammation and pain. Thus, Dr. Gonzales decided to treat his knee with VetStem Cell Therapy. When she collected a sample of his abdominal fat for stem cell processing, she also took biopsies of his intestines, which allowed her to officially diagnose him with Inflammatory Bowel Disease (IBD).

For his initial stem cell treatment, Finn received one dose of his own stem cells into his injured knee. He also received an intravenous dose. Stem cells have demonstrated the ability to home, or migrate, to areas of inflammation. Thus, we can assume that, when given intravenously, the stem cells would migrate to his knee and/or other areas that may have been inflamed. Within two weeks, Finn was noticeably more comfortable. His pain and lameness were much improved.

Approximately six weeks after his initial treatment, Dr. Gonzales noticed that Finn’s intestinal symptoms had also improved. According to Dr. Gonzales, his diarrhea resolved completely, and he was finally able to reach his ideal body weight. She also noticed improvements in his blood parameters.

Dr. Gonzales treated Finn with another dose of IV stem cells, this time specifically for IBD, approximately six months after his first treatment. She gave him a third IV dose approximately five months after his second. Finn has since experienced sustained control of his symptoms, he has maintained an ideal body weight, and he is now able to tolerate a greater variety of food ingredients without them upsetting his stomach.

IBD can be a frustrating disease. A definitive diagnosis can be time-consuming and costly, traditional treatments are life-long and can be complex, and the animal often continues to experience symptoms of the disease. Several dogs and cats have received VetStem Cell Therapy for IBD and have experienced an improvement in symptoms. Stem cells have shown to down-regulate inflammation, modulate the immune system, and repair damaged tissue, all of which can contribute to healing inflamed and diseased intestines. If your pet has IBD, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy. Or contact us to receive a list of VetStem providers near you.

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Mar 4, 2022

VetStem Cell Therapy for Elephant Viral Disease

Posted by Bob under VetStem Cell Therapy

Recently, VetStem CEO and founder, Dr. Bob Harman, was invited to present data at a global symposium for a deadly elephant virus known as Elephant Endotheliotropic Herpesvirus (EEHV). EEHV is a lethal viral infection that affects Asian elephants and now, increasingly, African elephants and can cause a highly fatal hemorrhagic disease.

The symposium was a three-day virtual event put on by the North American EEHV Advisory Group. It is a meeting where top researchers, veterinarians, and elephant husbandry colleagues from across the globe get together to present case reports, research findings, vaccine research, and treatment options. The EEHV Advisory Group aims to decrease elephant sickness and death due to EEHV and to provide “peer-reviewed, accurate information that reflects current thinking on the research and management of EEHV in both wild and captive elephants globally.”

Dr. Harman was invited to speak about the use of VetStem Cell Therapy in elephants afflicted with EEHV. VetStem has provided stem cell doses to several zoos in the United States who had elephants with EEHV and has gathered some promising data. While it is still very early, we are optimistic that stem cell therapy may be a viable treatment option for elephants with EEHV. Stem cells have numerous mechanisms of action, including the secretion of molecules that are anti-viral. In this limited set of elephants with severe EEHV, the stem cells seemed to be very effective though much research is still needed to verify the proper dose and timing of this novel therapy.

Interestingly enough, the idea to treat EEHV with stem cells came from our human clinical trial for COVID-19. As you may know, our human company, Personalized Stem Cells, developed and secured FDA approval for a stem cell clinical trial to treat COVID-19. The initial Phase 1 clinical trial, which was licensed to and conducted by Sorrento Therapeutics, had an extremely positive safety and efficacy profile and resulted in multiple ongoing Phase 2 clinical trials.

VetStem invites inquiries from public and private zoos across the United States who have questions or interest in participating in this novel stem cell EEHV therapy development with VetStem’s veterinary research team. Contact VetStem directly here.

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Feb 25, 2022

VetStem Helps Dog with Partial Cruciate Ligament Tear

Unfortunately, it’s not an uncommon story. A dog is running and playing and suddenly starts limping or holding one of their back legs up as if hurt. Usually, a trip to the veterinarian is in order. That’s exactly what happened to Belle, a mixed-breed dog, who was approximately 9 years old when she injured her knee. A trip to her veterinarian revealed that she had partially torn her cruciate ligament and also had osteoarthritis in her left knee.

Cruciate Ligament Injuries in Dogs

Cruciate ligament rupture is one of the most common reasons for hind limb lameness, pain, and subsequent knee arthritis in dogs. Additionally, according to the American College of Veterinary Surgeons, 40-60% of dogs who injure one cruciate ligament will go on to injure the other cruciate ligament in the future. While there are multiple treatment options available, both surgical and non-surgical, treatment with stem cells may accelerate and improve healing within the joint.

VetStem Cell Therapy for Partial Cruciate Ligament Tears

Though full cruciate ligament tears often require surgical repair, partial tears can sometimes be treated successfully without surgery. Stem cells are regenerative cells that can differentiate into many tissue types, reduce pain and inflammation, help to restore range of motion, and stimulate regeneration of tendon, ligament, and joint tissues. Many dogs have received VetStem Cell Therapy for partial cruciate ligament tears and have experienced a better quality of life. Thus, Belle’s veterinarian, Dr. Jennifer Tate of Timberstone Vet, recommended treatment with VetStem Cell Therapy.

Belle Receives Treatment with VetStem Cell Therapy

Belle

To begin the process, Dr. Tate collected fat tissue from Belle’s abdomen during a minimally invasive anesthetic procedure. The fat tissue was shipped to the VetStem laboratory where lab technicians extracted and concentrated Belle’s stem and regenerative cells. Two stem cell injections were shipped to Dr. Tate for treatment while the rest were put into cryostorage. Approximately 48 hours after the initial fat collection procedure, Belle received one stem cell injection into her affected knee as well as one intravenous injection.

According to her owner, Belle had a great response to treatment with VetStem Cell Therapy. Her owner stated, “Choosing to do stem cell therapy for Belle was the best choice we could’ve made. Within a few months of treatment and recovery, she was back to her old self running and playing and patrolling her kingdom.” Approximately one year later, Belle received a similar stem cell treatment for her opposite knee. Using some of her stored stem cell doses from the initial procedure, Belle received one dose into her right knee and one intravenous dose. She recovered well from that procedure and, according to her owner, is a happy girl with great mobility.

If your dog has an injured cruciate ligament, speak with your veterinarian about the possibility of treating with VetStem Cell Therapy. Or contact us to receive a list of VetStem providers in your area.

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Jan 14, 2022

VetStem Helps Search and Rescue K9 Return to Work

Yana is a Search and Rescue K9 with a high drive to work. Unfortunately, she injured her iliopsoas, a group of muscles that function to externally rotate and flex the hip joint, similar to the hip flexor in people. These muscles are connected to the femur via a common tendon. Iliopsoas injuries most frequently occur at or near the muscle-tendon junction, which is referred to as “the weak link.”

After several weeks and three misdiagnoses, Yana was taken to a board-certified surgeon and experienced VetStem user, Dr. Kim Carlson. Dr. Carlson used ultrasound to diagnose Yana with a grade 2, or partial, iliopsoas tear and recommended treatment with VetStem Cell Therapy.

Yana

Fat tissue was extracted from Yana’s abdomen during a minimally invasive anesthetic procedure and overnighted to our laboratory. From there, VetStem lab technicians isolated Yana’s stem and regenerative cells from her fat tissue. These cells were divided into doses, and two stem cell injections were shipped to Dr. Carlson for treatment. Yana received one injection of her own stem cells into her injured iliopsoas and one intravenous injection. The rest of her cells were put into cryopreservation.

According to her owner, the months following Yana’s stem cell treatment were not easy and Yana’s healing process took a bit longer than anticipated because it was difficult to keep her quiet. She had to be kept on leash for almost a year, which is not ideal for a high-drive working dog. Approximately three months after her initial treatment, Yana received a follow up stem cell treatment, identical to her first, utilizing the stem cells that were cryogenically stored from the original fat tissue process.

Fortunately, the difficult rehabilitation process paid off. Dr. Carlson confirmed, via ultrasound, that Yana’s injury was healed, and Yana was able to get back to her very important work. Her owner stated, “It was a very difficult year for us, but I am very happy to say it was worth it. Yana returned to her work 11 months after injury and is her old, agile self!”

We absolutely love to hear stories about VetStem Cell Therapy helping working animals return to what they love to do. But stem cells can help companion animals too! If you think your pet may benefit from stem cell therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

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Nov 5, 2021

VetStem Cell Therapy Helps Senior Pets Too

Posted by Bob under Pets, VetStem Cell Therapy

November is National Senior Pet Month. According to the AVMA, cats and small dogs are generally considered seniors at the age of seven. Larger breed dogs tend to have shorter lifespans and are considered seniors around five to six years of age. Like people, an older pet is more likely to develop diseases such as heart, kidney, and liver disease as well as cancer and osteoarthritis (OA).

Will VetStem Cell Therapy Help My Senior Pet?

We are often asked whether VetStem Cell Therapy will help senior pets. Generally speaking, younger stem cells tend to be healthier and therefore may be more efficient at performing their various jobs. That being said, many senior pets have been treated with VetStem Cell Therapy and have experienced great results.

One example is Molly, a Labrador who received VetStem Cell Therapy when she was approximately twelve and a half years old. Molly had severe OA and a potential spinal condition that made her suddenly unable to walk or support herself. Her owners elected to have Molly treated with VetStem Cell Therapy and were very pleased with the results. Just two weeks after her stem cell injections, Molly was able to support her own weight with assistance. At her one-month recheck appointment, Molly was able to take a few steps. And just shy of two months post-stem cell therapy, Molly was walking on her own again. Her owner stated, “She is walking again on her own and without assistance, and she is definitely limping less on that front elbow. While we do realize at her age and the severity of arthritis in her joints that she won’t be a puppy again, I would definitely expect her to continue to improve and continue to be mobile. I would do this again for her in a heartbeat, and we are so thankful this technology exists. Thank you, VetStem, for giving us back our happy girl.”

VetStem Cell Therapy for Alternative Conditions in Seniors

As stated above, senior pets are more prone to organ diseases such as kidney failure. Fortunately, VetStem Cell Therapy may help with that too! Many patients, mostly cats but some dogs as well, have received stem cell therapy for kidney disease.

One such patient was a senior cat named Trinity. Trinity was twelve years old when she was diagnosed with renal disease. She had several symptoms including vomiting, not eating, lethargy, weakness, and weight loss. Additionally, she was uninterested and spent a lot of time hiding. Several months after treatment with VetStem Cell Therapy, Trinity’s bloodwork showed no signs of kidney disease. She started eating again and gained back all the weight she had lost. Her owner stated, “I’m so thankful that I’ve been able to spend so many more years with Trinity.”

So, as you can see, VetStem Cell Therapy isn’t just for young pets. Senior pets have benefitted from stem cell therapy too! If you think your senior pet may benefit from VetStem Cell Therapy, speak to your veterinarian, or contact us to receive a list of VetStem providers in your area.

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Oct 15, 2021

Agility Dog Returns to Competition after VetStem Cell Therapy

Charm is a nine-year-old dalmatian and accomplished agility champion. Though she has always had a strong will to perform, Charm has had a few setbacks along the way. In 2016, Charm partially tore her cruciate ligament in her left knee. After consulting with her veterinarian and doing some independent research, Charm’s owner elected to have Charm treated with platelet rich plasma (PRP) and VetStem Cell Therapy.

To begin the process, fat tissue was collected from Charm’s inguinal area during a minimally invasive anesthetic procedure. Once collected, the fat was aseptically packaged and shipped to the VetStem laboratory in Poway, California. VetStem lab technicians processed the fat to extract and concentrate the stem and regenerative cells contained therein. One stem cell injection was shipped to her veterinarian for treatment. Approximately 48 hours after the initial fat collection procedure, Charm received one dose of her own stem cells and PRP into her injured knee.

Charm

According to her owner, Charm recovered well and returned to agility five months later. Unfortunately, this then four-year-old active dog, continued to show signs of intermittent lameness and stiffness. Though her X-rays showed no arthritis, further testing revealed that Charm had Lyme disease. This helped to explain her lameness as a few of the common symptoms of Lyme disease in dogs are painful or swollen joints and lameness that comes and goes. Though there is limited data regarding stem cell therapy for Lyme disease, Charm’s owner elected to have her retreated with stem cells in an attempt to manage her symptoms.

Charm received a second round of stem cell injections approximately one year after her initial treatment. This time, she received one dose into her left knee and one intravenous dose in conjunction with PRP. She was also treated with homeopathic remedies, hydrotherapy, and strength training. According to her owner, Charm bounced back and returned to master level agility trials. Her owner stated, “She feels great, her quantitative Lyme levels are subclinical, and she is running, jumping, and playing like a puppy again.” She later went on to win Agility Champion of Canada Awards, 5th place at Agility Association Canada Nationals plus a Distance Log from the Dalmatian Club of Canada. Charm received a third round of stem cell injections, both in her left knee and intravenously, approximately two years later.

Fast forward another few years and Charm, being the active athlete that she is, injured the cruciate ligament in her right knee. Fortunately, she still had multiple stem cell doses cryopreserved. So, in January of this year, Charm received a stem cell injection into her right knee. Once again, her owner noticed marked improvement. She stated, “This now nine-year-old girl is feeling wonderful just 5 weeks after her stem cell injection and no signs of any arthritic pain!”

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Sep 24, 2021

Veterinary Pain Practitioner Uses VetStem Cell Therapy

Posted by Bob under Pain in Pets, VetStem Cell Therapy

As we wrap up Animal Pain Awareness Month, we wanted to share a success story from an experienced VetStem user and animal pain specialist. In case you missed our last few blogs about pain in pets, here is a brief recap:

  • September is Animal Pain Awareness Month, which was created by the International Veterinary Academy of Pain Management (IVAPM) in an effort to raise awareness and to help pet owners recognize and manage their pet’s pain.
  • Recognizing pain in pets – When it comes to pain in pets, it’s not always easy to tell that our animals are hurting. Some pets are masters at hiding their pain. But there are some tips and tricks to help determine if your pet might be in pain.
  • VetStem Cell Therapy for pain – Stem cells have shown the ability to directly modulate acute and chronic pain.

Veterinary Pain Specialists

Just like there are specialists for specific branches of medicine such as surgery and internal medicine, there are also specialists in veterinary pain management. The IVAPM offers a certification in pain management for veterinarians who have practiced and studied animal pain management. Below, we will introduce you to Dr. Jamie Gaynor, a Certified Veterinary Pain Practitioner (CVPP) and avid VetStem user.

Dr. Jamie Gaynor, DVM, DACVA, DACVPM

Dr. Gaynor is one of the first veterinarians to utilize VetStem Cell Therapy in dogs. He has been working with VetStem since 2006 and has provided VetStem cell processing services for nearly 200 patients. One of his patients, a Great Dane with a partially torn cruciate ligament, experienced great relief after receiving VetStem Cell Therapy. Read his story below:

Frank Experiences an Improved Quality of Life after Treatment with VetStem Cell Therapy

Frank is an albino, deaf Great Dane. His owners rescued him when he was four months old from a breeder who did not want him due to his health issues. Despite his hearing impairment, he was always an active and playful pup. Frank bonded with his brother, another Great Dane named Tom, and the two would play all day, every day. As the two grew, playtime became rougher, and Frank ended up injuring his right rear leg.

Frank

Once diagnosed with a partially torn cruciate ligament, Frank underwent two years of physical rehabilitation. Though he showed a lot of improvement, VetStem Regenerative Cell Therapy came up as a potential option to treat the arthritis that formed in Frank’s stifle as a result of his injury. Frank was referred to Dr. Gaynor and his owner elected to move forward with the stem cell procedure.

In a minimally invasive anesthetic procedure, fat was collected from Frank’s abdomen and shipped off to the VetStem laboratory in San Diego, California. Upon receipt, the fat was aseptically processed to extract the stem cells and injectable doses of Frank’s own stem and regenerative cells were created. Three doses were shipped back to Dr. Gaynor and Frank received one injection into each knee and one intravenous injection.

According to Frank’s owner, Frank showed major improvement less than three months after receiving stem cells. His owner stated, “Actually, Frank was acting like a puppy again. His energy level went up, he became more involved and interested in daily activities. He started playing with his brothers again, he rebuilt his confidence with stairs and jumping into the car and on the couch. Most of all, we have not seen him limp once since his stem cell treatment…He truly is back to his old self again.”

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