VetStem founder and CEO, Dr. Bob Harman, recently joined Fuzzybutts and Friends on a podcast to discuss VetStem Cell Therapy and the science of stem cells. Joining him is Dr. Angie Zinkus, veterinarian and VetStem enthusiast at Germantown Parkway Animal Hospital. This podcast really gets down to the nitty gritty about stem cells and the various diseases that have been treated with VetStem Cell Therapy. Some of the big questions that are addressed are:

What are stem cells? Where do they come from? What are the mechanisms of action/how do they work? What CAN’T be treated with stem cells? And more!! You don’t want to miss this one!

Click the image below to check out the podcast:

All of us have heard the term “stem cells” and most of us have some basic understanding of what that means. Stem cells are often referred to as the building blocks of life. Thus, when it comes to stem cells, many people think of embryonic stem cells. But when we talk about VetStem Cell Therapy, we’re actually talking about adult stem cells.

Adult Stem Cells vs. Embryonic Stem Cells

There are several differences between embryonic and adult stem cells. Embryonic stem cells serve one purpose: to form whole organs and organisms. They are truly the “building blocks of life.” Embryonic stem cells exist only at the earliest stages of development, and they are pluripotent, meaning they can differentiate into any cell type.

Adult stem cells on the other hand include multiple types of stem cells that are present in almost all tissues of the adult body. They can be multipotent or unipotent, meaning they can only differentiate into one type of cell. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that have demonstrated the ability to differentiate into multiple cell types including tendon, ligament, bone, cartilage, cardiac, nerve, muscle, blood vessels, fat, and liver tissue.

Adult Stem Cells Mechanisms of Action

Adult stem cells are utilized by the body to replenish dying cells and to repair damaged tissues. This discovery led to multiple studies to help determine the full therapeutic benefits of adult stem cells. VetStem uses adult MSCs in an effort to repair damaged tissues in animals with various injuries and diseases. But this is not the only mechanism of action that stem cells utilize in the healing process. Stem cells have also been shown to down-regulate inflammation, reduce pain, and modulate the immune system. All of these mechanisms, and more that we’re still learning about, make stem cell therapy a multimodal approach to healing.

Ideal Source of Adult Stem Cells

When used for VetStem Cell Therapy, adult MSCs are extracted from fat tissue, one of the richest sources of MSCs in the body. Fat tissue is also relatively easy to collect during a simple anesthetic procedure similar to a spay. Most animals recover quickly and uneventfully from the procedure, compared to more painful and invasive stem cell collection techniques. Additionally, fat is generally abundant in the body, even in skinny animals, making it an ideal source of stem cells.

If you think your pet may benefit from VetStem Cell Therapy, contact us to receive a list of providers in your area.  

Much of our blog is dedicated to the various disease processes that can potentially be treated with VetStem Cell Therapy. But it’s been a while since we’ve discussed the basics of stem cells. What are stem cells? What purpose do they serve? We will answer these questions and more in this week’s blog.

What are stem cells?

Stem cells are specialized cells that have the ability to differentiate into over 200 types of known cells in the human body. Some of these cells include tendon, ligament, bone, cartilage, cardiac, nerve, muscle, blood vessels, fat, and liver tissue. Because of this, some have referred to stem cells as “the building blocks of life.”

When we think of stem cells as building blocks, we are most likely thinking of embryonic stem cells. Embryonic stem cells exist only at the earliest stages of development. They are pluripotent, meaning they can differentiate into any cell type. The function of embryonic stem cells is to form whole organs and organisms.

Alternatively, adult stem cells include multiple types of stem cells that are present in almost all tissues of the adult body. They can be multipotent or unipotent, meaning they can only differentiate into one type of cell. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that have demonstrated the ability to differentiate into multiple cell types. When used for VetStem Cell Therapy, adult MSCs are extracted from fat tissue, one of the richest sources of MSCs in the body.

What purpose do stem cells serve?

As mentioned above, embryonic stem cells serve one purpose: to form whole organs and organisms. Adult stem cells on the other hand, are utilized by the body to replenish dying cells and to repair damaged tissues. This discovery is what led to multiple studies to help determine the full therapeutic benefits of adult stem cells.

VetStem Cell Therapy: A Therapeutic Application of Stem Cells

VetStem uses adult MSCs in an effort to repair damaged tissues in animals with various injuries and diseases. But this is not the only mechanism of action that stem cells utilize in the healing process. Stem cells have also been shown to down-regulate inflammation, reduce pain, and modulate the immune system. All of these mechanisms, and more that we’re still learning about, make stem cell therapy a multimodal approach to healing.

If you think your pet may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

As leaders in the field of regenerative veterinary medicine, we are proud to announce that we have reached a new stem cell processing milestone. VetStem has processed over 15,000 patient samples resulting in over 35,000 stem cell treatments for animals across the United States and Canada. Over 2,200 veterinarians have utilized VetStem Cell Therapy processing services for their patients.

The majority of these treatments have been for orthopedic conditions such as osteoarthritis as well as injured tendons and ligaments in dogs, cats, and horses. We have also provided cell therapy services for patients with alternate conditions such as renal disease, inflammatory bowel disease, gingivostomatitis, spinal conditions, and more as part of our clinical research programs.

While most know that we primarily work with domestic animals, we also work with multiple exotic animal organizations and their programs to provide stem cell therapy for several exotic species. To date, nearly 200 exotic animals have been treated. Those animals include elephants, cheetahs, rhinos, several species of bears, giraffes, penguins, dolphins and more.

We are very proud to be leaders in this field of cutting-edge medicine. And we look forward to what the future holds! That being said, we wouldn’t be where we are without all of YOU, our pet owners and veterinary clients, who have trusted VetStem to handle your pets’ and patients’ stem cells over the past nearly two decades. Thank you from the bottom of our hearts!

VetStem founder and CEO, Dr. Bob Harman, was recently featured on a San Diego-based podcast to discuss all things stem cells, including the current COVID-19 clinical trial developed by our human company, Personalized Stem Cells.

One Medicine: Animal Data Helping People

We have previously blogged about a concept we call “One Medicine,” also known as translational medicine, in which advances in the veterinary field lead to advances in human medicine. In the last year, this notion has really come to the forefront, as we were hit with the COVID-19 pandemic.

It is very common for human scientists and doctors to review data obtained from animals when developing a new drug or technology. In a previous blog, we discussed how animal data was utilized to expedite development of a COVID-19 vaccine. Additionally, evaluation of COVID-19 positive animals has helped researchers understand how the virus functions and how it is transmitted in various species.

Data from VetStem Patients Helps People with COVID-19

VetStem has also joined the ranks in the fight against COVID-19. In fact, it was VetStem’s 15+ years of veterinary stem cell data that led to the development of an FDA approved COVID-19 stem cell clinical trial in human patients. Our human stem cell company, Personalized Stem Cells, Inc., developed and received FDA approval for the clinical trial and then licensed it to Sorrento Therapeutics. The study is well underway and the preliminary results look very promising.

In addition to discussing our contributions to the COVID-19 clinical trial, Dr. Harman also discussed our work with exotics organizations and specifically mentions helping an arthritic Sun Bear at the San Diego Zoo. He gives a bit of history regarding VetStem’s formation, treating his border collie Ben, as well as his own treatment with stem cell therapy for a rotator cuff injury.

Click here to listen to the podcast!

If you have some time, click the picture below to view a recent webinar from VetStem CEO Dr. Bob Harman. Dr. Harman discusses VetStem Cell Therapy in depth and also gives tons of information about our human stem cell studies including an upcoming FDA approved COVID-19 clinical trial.

In this video you will learn the history of VetStem and what stem cells do to promote healing. You will also learn about the various diseases VetStem Cell Therapy has been used for. If you skip ahead to approximately 14:50, Dr. Harman shifts to discuss our human stem cell company, Personalized Stem Cells, Inc. At approximately 19:00 Dr. Harman begins talking about PSC’s upcoming FDA approved COVID-19 trial. He provides information about recent stem cell studies for COVID-19 and details about the PSC study. You don’t want to miss this!