As 2020 comes to an end, we would like to focus our last blog of the year on the history and successes of VetStem Biopharma.

VetStem was born in 2002 with a dream to deliver regenerative medicine services and products to improve the lives of horses. It expanded shortly thereafter to provide regenerative medicine to small animals. By 2007 we had launched a full dog and cat program. In 2012 we started to respond to requests from zoos and aquatic animal parks to provide for their wild and exotic animal needs.

In the past 18 years, VetStem’s dedicated staff have provided veterinary regenerative medicine services for nearly 14,000 patients. We have focused on providing high quality cell therapy treatments and products such as the V-PET and Genesis platelet therapy systems. In our quest to spread regenerative medicine knowledge to veterinarians and pet owner, we have attended hundreds of conferences, produced 15 peer-reviewed papers and book chapters, and have spoken at conferences and clinics hundreds of times. Our first-of-its-kind regenerative medicine online training course has provided formal continuing education for over 5,000 veterinarians in the U.S. and abroad. 

In 2018 we decided the time was right to launch our own human stem cell company, and Personalized Stem Cells (PSC) was born. The mission was to use the years of VetStem animal safety and efficacy data to add human stem cell medicine to our portfolio. We are completing our first FDA approved study of knee arthritis this month and have developed an entire FDA program for treating COVID-19 patients, which we have licensed to Sorrento Therapeutics. Our plan is to move into traumatic brain injury in 2021.

This year, we also announced the launch of our contract manufacturing business, commonly called a CMO or CDMO, and we have christened this division Performance Cell Manufacturing (PCM). This was an opportunistic move to use our beautiful FDA GMP manufacturing plant and cell manufacturing experience to make important cell therapy products for other companies for use in clinical trials. 

PSC and PCM have brought revenue to VetStem and allowed us to grow, hire, and weather the COVID-19 storm, however, the human division would not exist without the years of animal cell therapy work and dedication of our employees through some tough economic times. Our animal health services are the foundation of everything that we have built, and we try to convey the importance of our veterinary business with the images in our front lobby (see below).

I believe in One Medicine, where the learning in the veterinary world supports animals and provides crucial information for human medicine. But I am, and always will be, a veterinarian first. We sincerely thank all of our dedicated customers, veterinarians and pet owners alike, and wish everyone the happiest of holidays. May 2021 bring health and happiness to all.   

We recently reached our 15 year anniversary as a member of Biocom, a life science association. Biocom is an organization that supports the life sciences on many fronts and in multiple locations. While Biocom is primarily based in California, they also have locations in Washington D.C. and Tokyo. From their website, “Biocom harnesses the collective power and experience of the most innovative and productive life science clusters in the world, with powerful advocacy and transformative programs to help companies in their quest to improve the human condition. Biocom provides the strongest public voice for research institutions and companies that fuel the California economy.”

As a member-driven organization, Biocom provides life science companies with the opportunities and resources they need to fulfill business goals. Biocom is great for networking and connecting companies in the San Diego area. Local area members include businesses in the biotechnology, pharmaceutical, genomics, diagnostic, medical device, connected health, agriculture, and bio-renewable energy fields. Their website states, “With 23 years in San Diego, Biocom is well known for its collaborative spirit and integral role in ensuring the life science ecosystem of San Diego has the support it needs to thrive, including infrastructure, networking, professional development, and business-friendly government regulations.”

VetStem CEO, Dr. Bob Harman, has a long history as a Biocom member. In the early 90s, Dr. Harman ran HTI Bio-Services, a contract research company, and regularly networked with other local biotech CEOs and entrepreneurs. Regarding those early days as a Biocom member, Dr. Harman stated, “These were exciting times not only because of technical innovation, but also because we were forming a community that helped to advance medicine and create a vital segment in the local and regional economy.”

VetStem endeavors to stay at the forefront of the field. Founded in 2002, VetStem is the first US-based commercial veterinary adipose stem cell company. We have processed fat tissue from nearly 14,000 patients resulting in over 30,000 stem cell treatments. In 2018, we utilized our over 15 years of experience and data in veterinary medicine to spin out a human stem cell company, Personalized Stem Cells, Inc. We also just announced the launch of our contract cell manufacturing business, which we will discuss in an upcoming blog. We are very proud to be a longtime member of Biocom and of our contributions to the biotech community.

It is officially December and we all know what that means: it’s National Cat Lovers’ Month! To celebrate, we have a special feline success story to share. You may remember from previous blogs such as this one, that many veterinarians use VetStem Cell Therapy to treat a number of internal medicine conditions in cats including kidney disease. One such patient is Kitters, who received VetStem Cell Therapy for kidney disease over seven years ago!

Symptoms and Diagnosis

At the age of 15, Kitters was diagnosed with kidney disease. He exhibited many of the common symptoms of renal failure such as lack of appetite, excessive thirst, nausea, lethargy, and weight loss. He was prescribed a typical protocol for kidney disease which included a prescription, low protein diet and subcutaneous fluids. While these treatments can potentially slow the progression of the disease, they will not reverse it.

Treatment with VetStem Cell Therapy

Fortunately for Kitters, his owner found a veterinarian who was willing to try VetStem Cell Therapy to potentially help him feel better. She drove Kitters from Los Angeles to Oakland, California to visit Dr. Gary Richter of Montclair Veterinary Hospital. Kitters underwent a fat tissue collection procedure to begin the VetStem process. His fat was processed at our laboratory where his stem and regenerative cells were extracted and concentrated. An injectable dose of Kitters’ stem cells was shipped back to Dr. Richter for intravenous injection back into Kitters. Two weeks later, he received a follow up intravenous injection.

Feeling Like Himself Again

Approximately 35 days after treatment with stem cells, Kitters was clearly feeling better. He was eating more, his energy was up, and he began putting on the weight he previously lost. His blood kidney values also went down after treatment. His mom made a great and very informative video documenting Kitters’ journey. You can watch it here.

VetStem Cell Therapy for Feline Kidney Disease

Kitters was originally treated back in 2013, and though he was not the first cat to receive VetStem Cell Therapy for kidney disease, many veterinarians were not aware of this potential treatment option back then. In recent years however, more and more veterinarians are beginning to offer VetStem Cell Therapy for both cats and dogs with kidney disease. As of December 2020, nearly 200 cats have received VetStem Cell Therapy for kidney disease and the outcome data collected from these cases appears promising.

If your cat has kidney disease, speak to your veterinarian to see if VetStem Cell Therapy may help. You can also contact us to find a VetStem provider near you.