Archive for May, 2020

May 29, 2020

VetStem Biopharma Centennial Club

As the first company in the United States to provide adipose-derived stem cell processing services to veterinarians and their patients, VetStem pioneered the use of regenerative stem cells in veterinary medicine. Since 2003, VetStem has trained nearly 5,000 veterinarians across the United States and Canada to perform VetStem Cell Therapy. We have processed fat samples for over 14,000 patients and 30 different species of animals.

Twelve of our VetStem trained veterinarians have provided VetStem services for over 100 of their patients. The “Centennial Club,” as we like to call them, are among the most experienced adipose-derived stem cell providers in the country. Seven of the Centennial Club members are small animal veterinarians while the other five are equine veterinarians. The Centennial Club members are:

Small Animal
Dr. Kim Carlson of North Peninsula Veterinary Surgical Group
Dr. Jamie Gaynor of Peak Performance Veterinary Group
Dr. Jeff Christiansen of Superior Veterinary Surgical Solutions
Dr. Allyson Berent of Animal Medical Center of New York
Dr. Adam Gassel of Blue Pearl Pet Hospital of Irvine
Dr. Keith Clement of Burnt Hills Veterinary Hospital
Dr. Tim McCarthy formerly of Cascade Veterinary Referral Center

Equine
Dr. Ross Rich of Regenerative Therapy Consulting
Dr. Martin Gardner of Western Performance Equine
Dr. John McCarroll of Equine Medical Associates
Dr. Bill Hay of Tryon Equine Hospital
Dr. Scott Reiners of Mountain View Equine Hospital

Each of the above veterinarians has made VetStem Cell Therapy an integral part of their veterinary practice. They are all experienced in case selection and have seen many positive outcomes. We think it’s worth mentioning that two of the above veterinarians have reached even bigger milestones. Dr. Martin Gardner has surpassed 500 stem cell cases and Dr. John McCarroll has over 250 stem cell cases. Additionally, there are four more veterinarians who are approaching 100 stem cell cases.

Stem cells are regenerative cells that can differentiate into many tissue types. In both small animals and horses, stem cell therapy is most often used to treat orthopedic conditions such as osteoarthritis and injured tendons and ligaments. VetStem Cell Therapy has shown to reduce pain and lameness and improve quality of life and return to work for horses. If you would like to locate a VetStem provider near you, please contact us.

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May 22, 2020

VetStem CEO Joins ACRM Board of Directors

The American College of Regenerative Medicine (ACRM) has asked VetStem CEO, Dr. Bob Harman, to join their board of directors. As the CEO and co-founder of both VetStem and human subsidiary, Personalized Stem Cells, Inc. (PSC), Dr. Harman has nearly two decades of experience working with stem cells and regenerative medicine.

VetStem CEO, Dr. Bob Harman

The first of its kind, the ACRM is a multi-specialty, interdisciplinary medical organization. The ACRM was formed to promote the science and ethical use of regenerative medicine with a strong emphasis on global interdisciplinary collaboration. Board members include medical doctors and surgeons, a dentist, a registered nurse and our very own veterinarian, Dr. Harman.

The ACRM’s mission statement encompasses everything from physician and patient education to safety and scientific advancement. While regenerative medicine and stem cell therapy is not new, there is still much to learn about regenerative cell therapies. The ACRM is fully committed to patient safety and a high standard of care. Like VetStem and PSC, the ACRM advocates for patient safety by following FDA guidelines and maintaining compliance.

The interdisciplinary focus of the ACRM will allow for the amalgamation of knowledge and expertise from doctors across multiple fields. Dr. Harman brings nearly two decades of experience with regenerative medicine in the veterinary field to share. With the launch of PSC in 2018, Dr. Harman can also provide insight into human regenerative medicine and FDA approved stem cell clinical trials. We hope this “One Medicine” approach will ultimately lead to understanding regenerative cell therapies more fully and open the door for additional FDA approved regenerative treatment options.

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May 15, 2020

The Importance of Storing Stem Cells

Posted by Bob under Dog Stem Cells, Stem Cell Storage

At VetStem, we have the potential to store stem cells from each patient whose fat we process. It is our general protocol to store a small number of stem cells from each fat sample for potential future use. Known as the Retention Sample, this small number of cells affords us the ability to provide stem cell treatments for the life of the patient from whom the cells came. More on that later.

Storage of Stem Cell Doses for Future Use

In addition to the Retention Sample, VetStem has the ability to store any unused stem cell doses from the initial stem cell process. How does this work exactly? Let’s say your dog has bilateral hip dysplasia and osteoarthritis and your veterinarian plans to give your dog an injection of stem cells directly into each hip as well as an intravenous injection. Three injections equals three doses. But suppose the fat sample from your dog had enough cells to provide six doses. Well, those extra three doses would then be cryopreserved for potential future use. And then down the line, if your dog started showing signs of discomfort, your veterinarian could request those three doses for a second stem cell treatment.

The Retention Sample Can Be Used to Provide More Doses

In keeping with this same scenario, your dog has now had two rounds of treatment, three injections each time. Therefore, all six doses from the initial fat processing have now been used. That is where the Retention Sample comes in. Our standard protocol is to store a small number of cells from every fat sample that we process. For a fee, the Retention Sample can be put into culture to grow more stem cells. The cultured stem cells will be genetically identical to your dog’s original stem cells. And once the culture process is complete (it takes approximately 3-4 weeks), your dog will have usable stem cell doses again.

Cryopreservation of Stem Cells

Cryopreservation of stem cells allows the cells to maintain their functional properties. When stored at very low temperatures, the cells can be stored for long periods. Normal biological processes are slowed allowing the regenerative properties of stem cells to remain intact. Cryopreserved cells will last the lifetime of your pet.

With the ability to culture and store extra stem cell doses, your pet should only have to undergo one fat collection procedure. Having extra doses available for use also eliminates waiting time. We ship stem cell doses out Monday through Friday and can work with short notice in most cases. This is especially beneficial for some of the animals who are battling life threatening conditions such as kidney disease.

If your pet has cells stored at VetStem and you have questions regarding those stored cells, do not hesitate to contact us! We can be reached by phone at 858-748-2004, email, or through our contact page. Alternatively, if you would like to receive a list of VetStem providers in your area, contact us here.

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May 8, 2020

An Update Regarding Pets and COVID-19

Posted by Bob under COVID-19

In a recent blog, we discussed animals from around the world who tested positive for COVID-19. To summarize, the number of positive cases were few and all shared one commonality: they were in close contact with a human caregiver/owner who was infected with COVID-19. Of the small number of cases, even fewer showed clinical signs. While one 17-year-old dog passed away, it was presumed that he died from ongoing health issues and other age-related concerns. The rest of the animals recovered, or were expected to recover, without incident. According to the CDC, “Based on the limited information available to date, the risk of animals spreading COVID-19 to people is considered to be low.”

Lion at the Bronx Zoo

In the weeks since that blog was published, a small number of new cases have been reported. As reported in the previous blog, the first case that was confirmed and reported in the United States was a tiger at the Bronx Zoo. The tiger, along with several other large cats, developed a dry cough and reduced appetite. One of the affected large cats, a lion, was tested a few weeks after the tiger and tested positive for COVID-19. It is believed that the animals were infected by a human caregiver who did not have symptoms but was actively shedding the virus. The affected cats are reported to be recovering well and no other animals at the zoo have shown symptoms.

Two Cats in New York

In addition, two domestic cats in New York have now tested positive for COVID-19. The cats were from different households and cities and both showed symptoms of respiratory disease. One cat lives in a household with an owner who has COVID-19 and a second cat that has had no clinical signs of illness.

The second cat to test positive for COVID-19 in New York is an indoor/outdoor cat. The cat does not live with an owner who has a confirmed case of COVID-19. It is suspected that this cat contracted COVID-19 from an owner who was asymptomatic or from contact with the virus outside of the home.

Pug in North Carolina

Making headlines recently was a pug in North Carolina who showed symptoms of respiratory disease and tested positive for COVID-19. The pug’s human family all have COVID-19 however another dog and a cat in the same house were negative. His owners stated, “(The dog) licks all of our dinner plates and sleeps in my mom’s bed, and we’re the ones who put our faces into his face. So, it makes sense that he got (coronavirus).” Confirmatory testing is still being conducted at USDA’s National Veterinary Service Laboratory. If those tests are confirmed, the case will be reported to the OIE – the World Organization for Animal Health. Winston, the pug, is already doing better.

The number of animals who have tested positive for COVID-19 remains low, thus the CDC does not currently recommend routine testing. If your pet is exhibiting symptoms of infection, call your veterinary provider. If you or a family member is sick, the CDC recommends you avoid contact and practice cleanliness when interacting with your pets. The CDC also recommends keeping cats indoors and dogs on leashes, avoiding interaction between your pets and other pets/humans, and avoiding places like dog parks and other areas where people and dogs gather.

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May 1, 2020

PSC Prepares to Launch COVID-19 Clinical Trial – You Can Help

Posted by Bob under COVID-19, Stem Cell Therapy

Our human stem cell company, Personalized Stem Cells, Inc. (PSC), recently announced that they filed a request with the FDA for expedited review of an Investigational New Drug (IND) application for the treatment of COVID-19 patients with stem cells. PSC was asked by the White House Coronavirus Task Force to apply for expedited review through a new FDA program called the Coronavirus Therapeutic Accelerator Program (CTAP). CTAP was launched to help expedite the approval process of clinical trials for promising COVID-19 therapies.

Stem Cells for COVID-19

Recent studies evaluating the effects of stem cell therapy in COVID-19 patients have come out of China and Israel showing strikingly positive results. Stem cells have anti-inflammatory properties and the ability to reduce scar tissue formation. Stem cell therapy has the potential to reduce the serious lung complications that occur as a result of infection with COVID-19. The goal of treatment is to reduce time spent in the ICU, reduce ventilator needs, and increase chances of survival for seriously ill COVID-19 patients.

PSC has scaled up production of stem cells in their FDA-inspected facilities to be ready to provide stem cell treatments upon FDA approval. If approved, the initial COVID-19 clinical trial, termed “CoronaStem 1,” will provide treatment for twenty hospitalized COVID-19 patients with serious complications. The first trial will be conducted in a limited number of local San Diego hospitals. PSC anticipates additional approvals and potential compassionate use in the future to allow for many more patients to be treated.

How can you help?

As a small business, PSC is utilizing their own resources to ramp up stem cell production. However, supplies and laboratory technicians are necessary to further increase production of stem cells. PSC plans to provide stem cell treatments to COVID-19 patients at no cost to the patient which requires additional money to pay the doctors, nurses and other healthcare workers who will be performing the clinical trial. Thus, PSC is reaching out to the public for donations to help in this fight against COVID-19. Your tax-deductible donation will allow PSC to provide stem cell treatments for as many COVID-19 patients as possible. All donations will go towards increasing stem cell production and paying doctors, nurses, technicians, and all those involved in performing the medical procedures for the clinical trial.

While the COVID-19 pandemic has impacted us all, many of us are looking for ways in which we can help. PSC has partnered with the San Diego Foundation, a 501c3 organization, to collect tax-deductible donations to further PSC’s efforts. Learn more about how your donation can help PSC fight COVID-19.

You can make a difference! Click here to donate today.

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