This week, we would like to introduce you to one of VetStem’s most prolific users: Dr. Kim Carlson. Dr. Carlson practices in the Bay Area of California and recently opened her new surgical practice North Peninsula Veterinary Surgical Group in San Mateo, CA.  Dr. Carlson is a board-certified surgeon with a special interest in orthopedic surgery, oncologic surgery, trauma and wound management.

Dr. Carlson became credentialed to perform VetStem Cell Therapy in 2007 and has provided VetStem services for over 200 patients since!  Dr. Carlson also uses the Pall Veterinary Platelet Enhancement Therapy kit.  We asked Dr. Carlson a few questions about her use of VetStem Cell Therapy.  See her answers below.

Many of your stem cell patients receive VetStem Cell Therapy in conjunction with orthopedic surgery.  Do you recommend stem cell therapy with all of your orthopedic surgeries?  If so, why? 

Yes, I do.  Because of the regenerative power of stem cells.  Most patients having orthopedic surgery have some degree of OA or soft tissue injury.  The benefit of stem cell therapy is faster healing, more normal healing, decreased pain, reduced development of OA.  Stem cells have the ability to treat injuries and return patients to full function that didn’t have a good prognosis with traditional options.  Not only do I recommend stem cell therapy for my orthopedic patients but I also recommend stem cell therapy for my patients who are being treated with skin grafts or other wound treatments.

Please explain why VetStem is your go-to stem cell provider. 

Simple.  Quality control.

You have provided VetStem services for well over 200 patients.  What advice can you offer to pet parents who are considering stem cell therapy for their pet? 

It’s a great option.  I’ve treated two of my own pets.  If you don’t have pet insurance look into obtaining pet insurance that will cover stem cell therapy should you need it for your pet.  Not only can stem cells help your pet with their current injury but their cells will be banked for any potential future treatments.

If you’re located in the Bay Area and are considering stem cell therapy for your pet, Dr. Kim Carlson is a very experienced and knowledgeable surgeon and VetStem provider.

In previous blog posts, we discussed risk factors for osteoarthritis and how to reduce or delay the onset of osteoarthritis.  In both of those posts, we mentioned that a pet being overweight may contribute to his/her development of osteoarthritis. 

Unfortunately, it is estimated that approximately 56% of dogs and 60% of cats in the United States are overweight or obese.  But how can you tell if your pet is overweight?  Below are some tools to help you determine if your pet is overweight.

One way to tell if your pet is overweight is to determine your pet’s body condition score.  You can look this up online and find pictures of what your pet’s ideal body should look like.  Below is an example of a body score chart for dogs and cats.  What score does your pet receive?  If you’re not sure, your veterinarian can help to determine your pet’s body condition score.

Notice in the chart above, the pictures show the view of dogs and cats from the top.  Looking at your pet from above can be a helpful way to determine if your pet is overweight.  Like the chart above says, you should be able to feel your pet’s ribs but not see them.  There should be a slight layer of fat over your pet’s ribs.  Your pet should also taper at their waist- a bit like an hourglass shape.

Another sign that your pet is overweight is reduced stamina or increased lethargy.  Is your dog panting more or not able to walk as far?  Is your cat unable to jump up on furniture?  Note that these signs can also indicate other, more serious conditions so if you’re concerned about your pet’s behavior, take him/her to the vet.

Nobody wants to be told that their pet is overweight.  But it puts your pet at risk of many diseases so it should not be ignored.  In addition to osteoarthritis, obesity can lead to serious health conditions such as diabetes and cardiovascular disease.  Alternatively, your pet may be obese as a result of a health problem such as hypothyroidism or Cushing’s disease. 

If you believe your pet may be overweight, a visit to the veterinarian is probably in order.  Luckily, there are steps you can take to ensure your pet maintains an ideal weight or to help your pet lose weight.  Your vet can rule out underlying diseases and also help you establish a nutritionally sound diet as well as an exercise routine that is appropriate for your buddy.

In previous blogs, we have discussed stem cell therapy for non-standard indications, or what we call “compassionate use” cases.  These are cases where there is limited data to show that stem cell therapy is effective however what results we do have, may look promising.  Examples include kidney disease, canine back pain, as well as several other diseases/conditions for which stem cells may be beneficial.  One such indication is Immune Mediated Polyarthritis, or IMPA for short. 

While IMPA is a form of arthritis, it is not the typical osteoarthritis that stem cells are used for regularly.  Rather than being caused by a malformed joint, wear and tear or trauma, IMPA is caused by the patient’s own immune system.  It is important to note that polyarthritis can be caused by an infection in the patient’s body.  Distinguishing between an infection and IMPA is imperative because treatment options are very different.  In this blog, we will discuss stem cell therapy for the treatment of IMPA.

In patients with IMPA, the immune system creates an inflammatory response and inappropriately sends white blood cells to the joints.  This in turn causes inflammation, pain, swelling, and difficulty waking.  The reason it is called “Polyarthritis” is because many of the joints may be affected in patients with IMPA.  While this condition is more common in dogs, it can affect cats as well.  IMPA is similar to Rheumatoid arthritis in humans.

Immune mediated diseases can be some of the most challenging cases for veterinarians to treat.  There are few therapeutic options when it comes to regulating an aberrant immune system.  Common treatment options include immunosuppression, often with steroids.  As most of you know, steroid use comes with several negative side effects and is not ideal for long-term use in dogs and cats.

So how may VetStem Cell Therapy help?  Well, we know that stem cells play a key role in not only managing pain but also in down-regulating inflammation.  Perhaps most importantly for these cases, stem cells have demonstrated immunomodulatory characteristics and the ability to help balance a patient’s immune system.  The study of stem cells for immune mediated diseases in both animals and humans is ongoing. 

IMPA is not the only immune mediated disease being treated with stem cells, however.  Veterinarians have utilized VetStem Cell Therapy to treat an array of immune mediated diseases, and we continue to gather data and monitor patient outcomes.  Some additional examples of immune mediated diseases that veterinarians are treating with VetStem Cell Therapy include canine dry eye, inflammatory bowel disease in dogs and cats, as well as feline chronic gingivostomatitis.

If your dog or cat is suffering from IMPA or another immune mediated disease, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy.  Or you can contact us to receive a list of VetStem providers in your area.

As we shared in a recent blog, VetStem launched a human stem cell company known as Personalized Stem Cells, Inc (PSC) in late 2018.  PSC was founded to advance and legitimize human regenerative medicine through FDA approved clinical trials.  As such, it was announced in June that PSC submitted their first FDA-IND (“Investigational New Drug”) application for the treatment of osteoarthritis, with the first clinical trial to be for patients with OA in the knee.

In less than one year since the company’s formation, PSC recently announced that their application was approved for conducting clinical trials for the treatment of osteoarthritis using stem cells.  The fast approval was in large part due to VetStem’s extensive experience and data from stem cell therapy in the veterinary field.

This is the first of several planned INDs that PSC will seek FDA approval for.  Similar to the VetStem model, they plan to start with orthopedic conditions and eventually expand to include other medical conditions.  Like VetStem, PSC will follow strict quality control and safety protocols.

For the first clinical trial, PSC has enrolled a limited number of clinical sites around the U.S. to provide treatment for knee osteoarthritis using stem cells. The enrolled physicians are among the most experienced stem cell physicians in the country.  You can contact PSC for clinical trial information, clinical trial site locations, or investment information.

Osteoarthritis (OA) affects approximately one quarter of the dog population.  OA is a chronic disease that is characterized by cartilage loss and bone changes in the affected joint(s).  Symptoms include painful joints and decreased or limited mobility.  While certain breeds of dogs, usually larger breed dogs, may be predisposed to developing OA, all dogs are at risk for developing this chronic condition.

Developing good habits early on may help to delay the onset of OA or may reduce the severity of the disease.  Below we have highlighted some general steps you can take to help prevent OA in your dog.  But remember, we advise that you first consult with your veterinarian to get a preventative plan tailored specifically to your dog.

Which brings us to our first step: regular veterinary visits.  Taking your dog to your vet for regular checkups may help to identify conditions that could lead to arthritis as well as identify arthritis early on in the disease process.  Your vet may be able to spot some of the earliest signs of OA even if your dog has not shown any typical symptoms such as limping or decreased mobility.  Early detection and treatment may help reduce the severity of damage to the joint(s).

Your veterinarian may also recommend a nutritionally sound diet for a slower rate of growth and joint supplements.  Joint supplements such as glucosamine and chondroitin can help to slow the loss of cartilage, the tissue that cushions your dog’s joints.  Omega-3 fatty acids may help reduce inflammation in the body.  It is best to speak to your veterinarian to determine which supplements and/or diet will be best for your dog. 

Exercise can also play an important role in reducing wear and tear on your dog’s joints.  Various breeds of dogs require different amounts and different types of exercise.  Work with your veterinarian to develop an exercise routine that is tailored to your dog.  By exercising your dog in the appropriate manner, you may be keeping them lean and building muscle which can help support their joints.

Keeping your dog at an ideal weight is essential in minimizing the wear and tear on your dog’s joints.  Like people, a dog’s body is not designed to carry too much extra weight.  When a dog is overweight, they are more likely to develop OA.  Speak with your veterinarian to develop a good nutritional plan for your dog to help maintain a healthy weight. If your dog has already been diagnosed with OA, speak to your veterinarian about the possibility of VetStem Cell Therapy.  Or contact us to receive a list of VetStem providers in your area.