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Aug 11, 2023

VetStem Cell Therapy for Feline Kidney Disease

VetStem Cell Therapy, while commonly used to treat orthopedic conditions in dogs and horses, has also been successfully used to treat a number of other diseases. One such disease is kidney disease in cats. Nearly 250 cats have received VetStem Cell Therapy for kidney disease.

Kidney disease is one of the most common causes of sickness and death in cats. Common symptoms can include weight loss, lethargy, variable appetite, and poor coat quality. Some cats may also drink and urinate more, vomit, or have diarrhea.

Unfortunately, treatment options for cats with kidney disease are limited and can be costly. The good news is, based upon our own data as well as the data of others, we believe that stem cells may help improve the symptoms and quality of life in some cats with kidney disease. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment.

Anecdotal data from pet owners and veterinarians suggests that treatment with VetStem Cell Therapy helps to improve symptoms associated with kidney disease. Owners have reported improved appetites, weight gain, and increased energy. That being said, more data is necessary regarding the use of VetStem Cell Therapy for cats with kidney disease. Thus, we continue to research the use of stem cells for this condition under one of VetStem’s clinical research programs.

If you think your cat may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of qualified VetStem providers near you.

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May 7, 2021

VetStem Cell Therapy for Canine Kidney Disease

We have discussed VetStem Cell Therapy for feline kidney disease many times on this blog. For a refresher and success stories, click here. But cats are not the only creatures to suffer from this potentially devastating disease. According to the International Renal Interest Society, “The prevalence of chronic kidney disease (CKD) has been estimated to be 0.5-1.0% in dogs.” While this may seem like a small number, that small percent of dogs may still suffer with a diagnosis like kidney disease.

Unfortunately, like with cats, treatment options for dogs with chronic kidney disease remain limited and can be costly or time consuming. Fortunately, VetStem Cell Therapy has shown some promise in the treatment of canine kidney disease. This is Abby’s story.

Abby

Abby is a basset hound mix who was diagnosed with renal disease when she was just one year old. According to her owner, she was very lethargic and would not eat or drink. With minimal treatment options, Abby’s owner elected to pursue treatment with VetStem Cell Therapy.

Abby had her fat collected and received her first stem cell treatment in August 2014. Due to the nature and severity of Abby’s condition, she went on to receive three more stem cell infusions in the four months following her initial treatment. Since then, Abby has continued to receive an intravenous injection of her own stem cells twice yearly and had her most recent treatment just three weeks ago.

According to Abby’s recent bloodwork, her kidney values are in the normal range. Her owner stated, “Six years later and she is doing great. She is a normal, happy healthy dog. I have her injected with her stem cells every six months and monitor her kidney levels through bloodwork twice a year.”

Of course, it is very heartwarming to hear a story like Abby’s. But each patient is different and stem cell therapy may not be an effective treatment option for all patients with kidney disease. If your pet has kidney disease, it is best to speak with your veterinarian to determine if stem cell therapy may be a good option for your pet. Or you can contact us to receive a list of VetStem providers in your area.

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Mar 19, 2021

Trinity Receives VetStem Cell Therapy for Feline Kidney Disease

Based on 15+ years of data, veterinarians primarily use VetStem Cell Therapy to treat dogs and horses. But cats have also benefited from stem cell therapy. In previous blogs, we have discussed stem cell therapy for various diseases in cats. For a good overview, read this blog.

VetStem Cell Therapy for Feline Kidney Disease

VetStem has processed nearly 400 feline fat samples to provide stem cells. Of these samples, over 50% have been for cats with kidney disease. Unfortunately, kidney failure may be the number one cause of sickness and death in older cats. Yet treatment options are limited and do not cure the disease.

Veterinarians have been treating feline kidney disease with VetStem Cell Therapy for over a decade. And we have seen some promising results! But nothing is as good as hearing about a kitty who experienced those results firsthand. This is Trinity’s story.

Symptoms, Diagnosis, and Treatment Plan

Trinity is a ragdoll cat who was diagnosed with renal failure when she was twelve years old. She had several symptoms including vomiting, not eating, lethargy, weakness, and weight loss. She was uninterested and spent a lot of time hiding. Her mom worked with several vets to find an effective treatment protocol for Trinity, but she continued to feel bad, and her blood kidney values kept going up.

Eventually, Trinity’s mom found Dr. Tamera Cole at The Animal Hospital at Steiner Ranch. Dr. Cole started Trinity on fluids and multiple medications to ease her symptoms and support her kidneys. Though Trinity’s mom noticed improvement, she continued to research additional treatment options.

Treatment with VetStem Cell Therapy

In her research, Trinity’s mom came across VetStem Cell Therapy and brought it up to Dr. Cole. Dr. Cole was already credentialed to perform the VetStem procedure and agreed that stem cell therapy may help Trinity.

She moved forward with the process and collected a sample of fat tissue from Trinity in a minimally invasive anesthetic procedure. The fat was processed at the VetStem laboratory and Trinity’s stem cells were extracted, concentrated, and divided into doses for treatment. Trinity received an intravenous dose of her own stem cells approximately 48 hours after the initial fat collection procedure. She went on to receive a second intravenous dose approximately two weeks later.

A brown and white ragdoll cat sitting in front of a computer looking at the camera
Trinity

Trinity Gets Her Quality of Life Back

After stem cell therapy, Trinity’s owner maintained the previous treatment protocol with fluids and medications. Several months later, Dr. Cole tested Trinity’s blood work which showed no signs of kidney disease!

Her owner continued the treatment protocol and Trinity remained healthy, started eating again, and gained back all the weight she lost and more. Trinity’s mom stated, “I’m so thankful that I’ve been able to spend so many more years with Trinity. She is a continuous blessing in my life and as you can see from the picture, still shows up to work every day at my home office.”

Trinity is among several cats who have benefitted from VetStem Cell Therapy for kidney disease. Based upon data from a small number of feline patients treated with VetStem Cell Therapy, blood kidney values were slightly to moderately improved after treatment. More evaluation is necessary, however these preliminary results suggest that stem cell therapy may be a viable treatment option for cats with kidney disease.

If your cat is suffering with kidney disease, speak to your veterinarian or contact us to receive a list of VetStem providers in your area to determine if VetStem Cell Therapy may help your cat.

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Dec 4, 2020

VetStem Cell Therapy Success Story: Feline Kidney Disease

It is officially December and we all know what that means: it’s National Cat Lovers’ Month! To celebrate, we have a special feline success story to share. You may remember from previous blogs such as this one, that many veterinarians use VetStem Cell Therapy to treat a number of internal medicine conditions in cats including kidney disease. One such patient is Kitters, who received VetStem Cell Therapy for kidney disease over seven years ago!

Symptoms and Diagnosis

At the age of 15, Kitters was diagnosed with kidney disease. He exhibited many of the common symptoms of renal failure such as lack of appetite, excessive thirst, nausea, lethargy, and weight loss. He was prescribed a typical protocol for kidney disease which included a prescription, low protein diet and subcutaneous fluids. While these treatments can potentially slow the progression of the disease, they will not reverse it.

Kitters receiving an IV dose of his own stem cells

Treatment with VetStem Cell Therapy

Fortunately for Kitters, his owner found a veterinarian who was willing to try VetStem Cell Therapy to potentially help him feel better. She drove Kitters from Los Angeles to Oakland, California to visit Dr. Gary Richter of Montclair Veterinary Hospital. Kitters underwent a fat tissue collection procedure to begin the VetStem process. His fat was processed at our laboratory where his stem and regenerative cells were extracted and concentrated. An injectable dose of Kitters’ stem cells was shipped back to Dr. Richter for intravenous injection back into Kitters. Two weeks later, he received a follow up intravenous injection.

Feeling Like Himself Again

Approximately 35 days after treatment with stem cells, Kitters was clearly feeling better. He was eating more, his energy was up, and he began putting on the weight he previously lost. His blood kidney values also went down after treatment. His mom made a great and very informative video documenting Kitters’ journey. You can watch it here.

VetStem Cell Therapy for Feline Kidney Disease

Kitters was originally treated back in 2013, and though he was not the first cat to receive VetStem Cell Therapy for kidney disease, many veterinarians were not aware of this potential treatment option back then. In recent years however, more and more veterinarians are beginning to offer VetStem Cell Therapy for both cats and dogs with kidney disease. As of December 2020, nearly 200 cats have received VetStem Cell Therapy for kidney disease and the outcome data collected from these cases appears promising.

If your cat has kidney disease, speak to your veterinarian to see if VetStem Cell Therapy may help. You can also contact us to find a VetStem provider near you.

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Jun 5, 2020

Success Story: VetStem Cell Therapy for Feline Kidney Disease

We’ve shared many blog posts about treating cats with stem cells. Although we primarily process fat from dogs and horses for VetStem Cell Therapy, we’ve provided cell processing services for over 350 cats. Like dogs, cats may benefit from VetStem Cell Therapy for the treatment of osteoarthritis. Veterinarians have also treated cats for a variety of internal medicine diseases utilizing VetStem Cell Therapy. These diseases include Gingivostomatitis, Inflammatory Bowel Disease, and Chronic Kidney Disease. For more information about stem cell therapy for these conditions, this blog is very helpful: Stem Cells for Cats: An Overview.

One VetStem recipient, a domestic short haired cat name Bender, received VetStem Cell Therapy for kidney disease and had a positive outcome. Bender’s renal issues began when he was four years old. He ingested an unknown poison and ended up in the emergency hospital on IV fluids for seven days. Following this episode, Bender’s bloodwork showed elevated kidney values and he was diagnosed with stage 3 kidney disease.

Bender

Bender’s owner began researching potential treatment options and came across the VetStem website. She requested a list of stem cell providers in her area and was referred to Dr. Mark Parchman of Bend Veterinary Specialty and Emergency Center. Together, Dr. Parchman and Bender’s owner agreed to move forward with VetStem Cell Therapy.

To begin the process, Dr. Parchman collected fat from Bender. This fat was shipped to the VetStem laboratory and aseptically processed to extract Bender’s stem and regenerative cells. These cells were divided into doses and one dose was shipped back to Dr. Parchman for treatment approximately 48 hours after the fat collection. Bender received a series of three intravenous doses one week apart. The rest of his doses were cryopreserved for future treatment.

Approximately six months after his third stem cell injection, Bender’s owner stated that, “By all appearances he seems happy, healthy, playful, and active. Though he has suffered some permanent kidney damage.”

Approximately two years after his initial round of stem cell injections, he received a follow up intravenous injection from his stem cell bank. That was over three years ago and according to his owner he’s still doing well. His owner stated, “Bender is stable with basically high normal values, lots of energy, playful and continues to do very well considering he was so near not surviving. I believe that stem cell treatments have helped his body recover and remain stable over five years later. Thank you VetStem for blazing a trail for my cat.”

Bender is not the only cat with kidney disease to benefit from VetStem Cell Therapy. Other cats have received VetStem Cell Therapy for the treatment of kidney disease and many have experienced positive outcomes. If your cat has kidney disease and you think VetStem Cell Therapy may help, contact us to receive a list of VetStem providers in your area.

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Oct 26, 2018

Stem Cell Therapy for Cats Part 1: Chronic Kidney Disease

Posted by Bob under Cat Stem Cells

A few weeks ago, we shared a blog post about stem cell therapy for arthritic cats.  Similar to stem cell therapy for dogs, there are additional common feline diseases for which stem cells may be beneficial.  These diseases include Chronic Kidney Disease (CKD), Inflammatory Bowel Disease (IBD), and Gingivostomatitis. VetStem is still evaluating the use of stem cells for these disease processes with some favorable results being seen.  In part one of this blog series, we will discuss feline Chronic Kidney Disease and how VetStem Regenerative Cell Therapy may provide some relief.

Chronic Kidney Disease is a major cause of morbidity and mortality in cats.  Common symptoms include lethargy, increased urine output, and weight loss.  Other than a kidney transplant, which is costly and invasive, there really is no definitive cure for CKD.  Current therapies include supportive measures such as subcutaneous fluids and special diets.  The disease process, however, will continue to progress.

VetStem veterinarians have seen some promising results in the treatment of feline CKD.  Based upon data from a small number of feline patients treated with VetStem Regenerative Cell Therapy, blood kidney values were slightly to moderately improved after treatment.  While more evaluation is necessary, these preliminary results suggest that stem cell therapy may be a low-risk treatment option for cats with CKD.

If your cat has Chronic Kidney Disease, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.  And stay tuned for part 2 of this blog series in which we will discuss stem cells for Inflammatory Bowel Disease.

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Jul 15, 2022

VetStem Cell Therapy for Immune-Mediated Disease

VetStem Cell Therapy is primarily used for the treatment of orthopedic conditions in dogs and horses. It is also used, with some frequency, for non-standard indications in cats such as chronic kidney disease and gingivostomatitis. Another non-standard indication that is treated in both dogs and cats, as you may remember from this previous blog, is inflammatory bowel disease.

These and other non-standard indications fall under VetStem’s clinical research department. This means that there are minimal published studies demonstrating effectiveness of stem cell therapy in the treatment of these diseases and VetStem is conducting their own research to help determine if stem cells are a viable treatment option. Clinical research cases are approved on a case-by-case basis, as stem cells are not appropriate for all disease processes.

Stem Cells Have Immunomodulatory Functions

The truth is, we don’t yet fully understand the entirety of what stem cells are capable of. That is one of the reasons why stem cell research for the treatment of various diseases is so important. While the research is ongoing, there is some evidence to suggest that stem cells have multiple immunomodulatory functions. That is, they have the ability to modulate the immune system. Thus, it makes sense that they may be helpful in controlling immune-mediated diseases.

VetStem Cell Therapy for Immune-Mediated Disease

Veterinarians have utilized VetStem Cell Therapy for a number of immune-mediated diseases. We mentioned a few of them earlier: gingivostomatitis and inflammatory bowel disease (IBD). That’s right, the literature suggests that both gingivostomatitis and IBD are immune-mediated diseases. Additional immune-mediated diseases that have been treated with VetStem Cell Therapy with some success include keratoconjunctivitis sicca (KCS, or dry eye), immune-mediated hemolytic anemia (IMHA), and immune-mediate polyarthritis (IMPA).

As we mentioned above, the research is ongoing so we can’t say with certainty that stem cell therapy will help in every case. Additionally, diseases present differently from patient to patient. Thus, treatment outcomes will also vary. Stem cell therapy is not a miracle cure-all treatment option. But it is a natural alternative to the potentially damaging immunosuppressive medications that are commonly used to treat immune-mediated diseases.

If you think your pet may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers in your area.

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Aug 6, 2021

VetStem Cell Therapy for Diseases in Cats

This coming Sunday, August 8th, is International Cat Day! We thought this would be the perfect opportunity to discuss the use of stem cells for various diseases in cats. Like dogs and horses, VetStem Cell Therapy can be used in cats to treat orthopedic conditions such as osteoarthritis and injured tendons and ligaments. But there are several other diseases for which VetStem Cell Therapy may be helpful.

Chronic Kidney Disease

A common disease in cats is kidney disease. Chronic Kidney Disease (CKD) is a common cause of sickness and death in cats. In fact, some reviews suggest that CKD may be the number one cause of sickness and death in older cats. Unfortunately, treatment options are limited and can be costly.

One potential treatment option is VetStem Cell Therapy. Nearly 200 cats have received VetStem Cell Therapy for CKD and veterinarians have seen some promising results. Based upon data from a small number of feline patients treated with VetStem Cell Therapy, blood kidney values were slightly to moderately improved after treatment. While more evaluation is necessary, these results suggest VetStem Cell Therapy may be a viable treatment option for cats with CKD.

Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is a gastrointestinal disease that can affect both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Several cats have received VetStem Cell Therapy for IBD. In fact, one of our veterinary clients, Dr. Joel Stone, wrote a guest blog about one of his feline patients who experienced relief from IBD after treatment with VetStem Cell Therapy. In one of our own case studies, a 4-year-old Himalayan cat developed IBD and treatment with VetStem Cell Therapy quickly resolved the cat’s diarrhea and vomiting and led to an increased appetite with no recurrence. To add to that, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells were significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

Gingivostomatitis

Another unfortunate disease that affects cats is gingivostomatitis. Gingivostomatitis affects the mouths of felines and causes oral pain which leads to other symptoms such as decreased appetite, reduced grooming, and weight loss. The most common treatment is extracting all the cat’s chewing teeth, however only about 70% of cats will respond to this treatment. The remaining 30% of cats that do not respond will require lifelong treatment with medications.

Fewer cats have received VetStem Cell Therapy for gingivostomatitis than CKD, however veterinarians have seen favorable results none the less. In addition to our own data, two small studies conducted at the University of California Davis showed that when fat-derived stem cell therapy was utilized in addition to teeth extractions, there was improvement or remission in the majority of cats treated. VetStem believes that fat-derived stem cell therapy without full extractions may be beneficial.

As you can see, VetStem Cell Therapy may be useful for a number of disease processes. Though the above conditions are still in the investigative stages, the preliminary results look very promising! If you think your cat may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us for a list of VetStem providers near you.

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Nov 2, 2018

Stem Cell Therapy for Cats Part 2: Inflammatory Bowel Disease

Posted by Bob under Cat Stem Cells, Stem Cell Therapy

Last week, we shared part 1 of this blog series regarding stem cells for cats.  While stem cells may be an effective treatment for arthritic felines, there are a few other diseases for which stem cells may be beneficial including Chronic Kidney Disease, Inflammatory Bowel Disease, and Gingivostomatitis.  In last week’s blog, we discussed Chronic Kidney Disease.  In part 2 of this series, we will look at Inflammatory Bowel Disease and how stem cells may be of benefit.

Inflammatory Bowel Disease (IBD) is a chronic gastrointestinal disorder characterized by inflammation in the gut.  Some of the common symptoms include diarrhea, vomiting, reduced appetite, and weight loss.  It is important to note however that these symptoms can be indicative of several various ailments such as food allergies, bacterial or viral infections, and intestinal parasites.  Typically, these problems can be resolved with dietary changes and/or antibiotics while IBD is generally responsive to immunosuppressive therapy such as steroids.

Also, when considering stem cell treatment for cats with IBD, it is necessary to rule out Lymphoma as the underlying cause of the symptoms.  VetStem Regenerative Cell Therapy is contraindicated in patients with active cancer.

In a case study where a 4-year-old Himalayan cat developed IBD, treatment with VetStem Regenerative Cell Therapy quickly resolved the cat’s diarrhea and vomiting and led to an increased appetite.  To add to that, in a recently published paper, 5 out of 7 cats that were treated with stem cells were significantly improved or had complete resolution of symptoms whereas the 4 control cats had no improvement.1

If your cat has Inflammatory Bowel Disease, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.  And stay tuned for part 3 of this blog series in which we will discuss stem cells for Gingivostomatitis.

Note: Dogs with IBD may benefit from stem cell therapy as well.

 

1. Webb, TL and Webb, CB (2015) Stem cell therapy in cats with chronic enteropathy: a proof-of-concept study. J Fel Medand Surg(10). 17, 901-908.

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Feb 7, 2025

National Cat Health Month: Stem Cell Therapy for Cats

Posted by Bob under Cat Stem Cells, Cats

As we celebrate National Cat Health Month, it’s important to recognize the silent struggles many cats face. Cats are notorious for hiding pain, a trait that evolved to protect them in the wild. Unfortunately, this means many conditions go unnoticed until they reach an advanced stage. One such condition is osteoarthritis, which affects a significant number of older cats but is often undiagnosed because the signs are subtle. Limping, reduced activity, and difficulty jumping may seem like just signs of aging, but these are often indications of joint pain. With VetStem Cell Therapy, cats suffering from osteoarthritis may find relief, as stem cells can help reduce pain and inflammation and promote tissue repair, thereby improving their mobility and comfort.

While stem cell therapy is widely known for treating joints and soft tissue injuries, its benefits extend beyond osteoarthritis. VetStem Cell Therapy has shown promise in treating alternative conditions like kidney disease, inflammatory bowel disease (IBD), and gingivostomatitis. Stem cells have unique regenerative properties that can help reduce inflammation and support tissue repair in the kidneys, intestines, and gums. For cats with chronic kidney disease, stem cell therapy may help slow the progression of the disease and improve quality of life. In cases of IBD, stem cells can help reduce gut inflammation and modulate the immune system, thereby reducing symptoms associated with the disease. The same is true for cats suffering from gingivostomatitis, a painful inflammatory condition affecting the mouth. Stem cell therapy can promote healing of the tissues, reduce pain, and control the immune response.

As cat owners, we want the best for our feline companions, and stem cell therapy is emerging as a promising solution for a variety of conditions. By leveraging the body’s regenerative abilities, stem cell therapy can not only improve the quality of life for cats but also help manage chronic conditions that have limited treatment options. This National Cat Health Month, consider discussing stem cell therapy with your veterinarian to learn how it might benefit your cat.

Contact us to receive a list of VetStem providers near you.

Smiling woman and her cat at the veterinary clinic, a doctor is examining the pet

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