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Jun 28, 2024

VetStem Cell Therapy for Gingivostomatitis: An Update on Finn

Posted by Bob under Cat Stem Cells, Gingivostomatitis

As most of our readers know, VetStem Cell Therapy is primarily used to treat orthopedic conditions in dogs and horses. Cats, on the other hand, frequently receive stem cell therapy for indications such as renal disease, inflammatory bowel disease, and gingivostomatitis. One such cat, a young Siamese named Finn, received VetStem Cell Therapy for gingivostomatitis when he was approximately one year old.

We’ve shared Finn’s stem cell success story in a previous blog. But to sum it up, Finn was diagnosed with gingivostomatitis at just five months old. Gingivostomatitis is a debilitating condition characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduced grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, pain medications, and/or full mouth teeth extractions.

Finn’s owners tried several medications in an effort to improve his symptoms, but nothing worked. They were determined to not have all of his teeth extracted and were willing to do whatever it took. His veterinarian recommended treatment with VetStem Cell Therapy and just shy of his first birthday, Finn received stem cell therapy.

According to his owners, Finn responded well to the treatment. His owner stated, “[the stem cell treatment] seemed to improve and maintain his condition especially over time so that Finn is happy, healthy, and living a great life. We plan to administer cells every year or so to keep his condition manageable and hopefully keep him healthier too.”

Fast forward to the present, four years after his initial stem cell treatment, and Finn continues to do well! We recently received an update from his owner who stated, “Finn had his annual checkup recently and he’s doing great. He had some gingivitis but his stomatitis seemed to be under control. He had his annual teeth cleaning today (per his veterinarian’s recommendation) and is doing great otherwise!”

Stem cells have shown the ability to reduce inflammation and also help to modulate the immune system. This mechanism of action is particularly important for immune-mediated conditions such as gingivostomatitis. If your cat has gingivostomatitis, VetStem Cell Therapy may help. Contact us to receive a list of providers near you.

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Jun 10, 2022

VetStem Cell Therapy Helps Cat with Gingivostomatitis

We’ve talked about treating feline gingivostomatitis with VetStem Cell Therapy a few times on this blog. But sometimes we need more than just the science to describe how this treatment can potentially help cats. So this time, we will share a success story. Finn is a Siamese cat with gingivostomatitis who experienced an improvement in his symptoms after treatment with VetStem Cell Therapy.

Gingivostomatitis Symptoms

At just five months old, Finn was diagnosed with gingivostomatitis. Gingivostomatitis is a debilitating condition characterized by chronic inflammation of the affected cat’s gums. It can be very painful and lead to inappetence, reduced grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, pain medications, and/or full mouth teeth extractions.

VetStem Cell Therapy for Gingivostomatitis

Current literature supports the notion that gingivostomatitis is an autoimmune disease. Mesenchymal stem cells have demonstrated the ability to migrate to areas of inflammation, down-regulate inflammation, modulate the immune system, stimulate neoangiogenesis (formation of new blood vessels), and repair damaged tissue. Additionally, a recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. While more research is needed, preliminary results suggest that VetStem Cell Therapy can improve the symptoms of some cats with gingivostomatitis.

Finn’s Treatment with VetStem Cell Therapy

Finn

Finn’s owners tried several medications in an effort to improve his symptoms, but nothing worked. They were determined to not have all of his teeth extracted and were willing to do whatever it took. His veterinarian recommended treatment with VetStem Cell Therapy and just shy of his first birthday, Finn received stem cell therapy.

To begin the process, fat was collected from Finn’s abdomen during a minimally invasive anesthetic procedure. The fat was sent to the VetStem processing laboratory. Lab technicians processed his fat to extract and concentrate his stem and regenerative cells and Finn received one intravenous injection of his own cells. Approximately four weeks later, Finn received a second intravenous dose using some of the stem cells banked from his initial fat collection.

According to his owners, Finn responded well to the treatment. His owner stated, “[the stem cell treatment] seemed to improve and maintain his condition especially over time so that Finn is happy, healthy, and living a great life. We plan to administer cells every year or so to keep his condition manageable and hopefully keep him healthier too.”

If your cat has gingivostomatitis, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy. Or contact us to receive a list of VetStem providers in your area.

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Nov 9, 2018

Stem Cell Therapy for Cats Part 3: Gingivostomatitis

Posted by Bob under Cat Stem Cells, Stem Cell Therapy

In our last two blog posts, we discussed stem cells for cats.  In addition to arthritis, stem cells may be beneficial for felines with Chronic Kidney Disease (CKD) and Inflammatory Bowel Disease (IBD).  In this week’s blog, we will discuss feline Gingivostomatitis.

Gingivostomatitis is a disease affecting the mouth of felines.  It causes oral pain which leads to other symptoms such as decreased appetite, reduced grooming, and weight loss.  The most common treatment is extracting all the cat’s teeth, however only about 70% of cats will respond to this treatment.  Those cats that do not respond will require lifelong treatment with medications.

Two small studies on cats that had full mouth extractions conducted at the University of California Davis have shown that fat-derived stem cell therapy led to improvement or remission in the majority of cats treated.  VetStem believes that fat-derived stem cells without full extractions may be beneficial.  While a few veterinarians have seen favorable results using VetStem cell therapy, more investigation is needed.

If your cat has Chronic Kidney Disease, Inflammatory Bowel Disease, or Gingivostomatitis, stem cell therapy may provide relief.  Contact us today to locate a VetStem Credentialed veterinarian in your area.

This concludes our “Stem Cell Therapy for Cats” blog series.  Thanks for reading!  If you have any questions, feel free to contact us at info@vetstem.com.

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Aug 23, 2024

VetStem Sponsors Fetch DVM360 Veterinary Conference

Posted by Bob under VetStem

This week, we are sponsoring, speaking, and exhibiting at the annual Fetch DVM360 Veterinary Conference in Kansas City, MO. This is our second time sponsoring this show in recent years. Veterinary conferences are a great way for us to get in front of our colleagues in the field to educate and further develop those relationships.

This year, Dr. Bob Harman will deliver two lectures at the conference. The first is about the many uses of platelet-rich plasma (PRP) in veterinary medicine. PRP is a cell-based therapy that has been used in veterinary medicine for healing in orthopedics, wounds, corneal ulcers, and more. Dr. Harman will examine the literature and present a few case studies to evaluate the safety and efficacy of PRP. He will also do a deep dive into our latest product, an off-the-shelf freeze-dried PRP, PrecisePRP™.

His second talk will delve into the world of stem cell therapy. Most of us know that stem cells are primarily used in orthopedics for things such as osteoarthritis and injured tendons/ligaments. But in recent years, stem cells have shown great promise in treating some complicated diseases such as kidney failure, inflammatory bowel disease, and gingivostomatitis. Numerous patients have benefited from treatment with VetStem Cell Therapy for these conditions.

If you happen to be at the show, come visit the VetStem team at booth #1200!

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Aug 9, 2024

FAQs about VetStem Cell Therapy for Pet Owners

While VetStem Cell Therapy has been around for over 20 years and used in over 16,000 animals, many pet owners are new to the idea of stem cell therapy. As pet owners explore this innovative therapeutic modality, it’s natural to have questions about its effectiveness, safety, and applications. Here, we address some common FAQs to provide clarity and insight into what stem cell therapy entails for your beloved companions.

1. What is stem cell therapy and how does it work for pets? Stem cell therapy involves using the regenerative properties of stem cells to promote healing and repair damaged tissues in pets. VetStem Cell Therapy utilizes a pet’s own stem cells from a sample of fat tissue that your veterinarian collects during a minimally invasive anesthetic procedure. After processing in our GMP compliant stem cell laboratory, the stem cells are prepared and shipped to your veterinarian for injection into the area(s) of injury/disease. (Learn more about the laboratory process here.) This process aims to reduce inflammation, relieve pain, and improve overall mobility and quality of life in pets suffering from conditions like osteoarthritis, tendon or ligament injuries, and even certain internal medicine and immune-mediated conditions.

2. Is stem cell therapy safe for pets? Stem cell therapy is considered safe for pets when performed by trained veterinary and laboratory professionals. VetStem Cell Therapy involves minimal risk because the stem cells are sourced from the pet’s own body, reducing the likelihood of rejection or adverse reactions. Additionally, stem cells processed at VetStem are minimally manipulated and undergo strict quality assessments. VetStem employs stringent processing protocols and quality control methods to help ensure the safety and well-being of the animal. However, as with any medical treatment, potential risks and benefits should be discussed with your veterinarian before proceeding.

3. What conditions can stem cell therapy treat in pets? Stem cell therapy has shown promise in treating a variety of conditions in pets, primarily those involving musculoskeletal and joint issues. Common applications include osteoarthritis, joint dysplasia, ligament and tendon injuries, and muscle injuries. Research is ongoing to explore its potential for treating other ailments such as kidney disease, gingivostomatitis, inflammatory bowel disease, and more! While results can vary depending on the severity of the condition and individual pet responses, many owners report improvements in their pet’s quality of life following stem cell treatment.

4. How much does stem cell therapy cost and is it covered by pet insurance? The cost of stem cell therapy for pets can vary widely depending on factors such as the type of condition treated, the clinic’s location, and the specific treatment protocol used. On average, pet owners can expect to invest several hundred to several thousand dollars per treatment session. It’s important to check with your veterinarian and inquire about potential financing options or payment plans that may be available. Regarding pet insurance coverage, policies can differ significantly, so it’s advisable to review your insurance policy or consult with your provider to determine if stem cell therapy is covered under your plan.

VetStem Cell Therapy has improved the lives of thousands of pets suffering from various medical conditions. By understanding the basics of this treatment option and discussing it with your veterinarian, you can make informed decisions about whether stem cell therapy is suitable for your pet’s specific needs. Click here to receive a list of VetStem providers near you.

A veterinarian in blue scrubs gives an IV injection of stem cells to a black and white pit bull.

VetStem patient, Bella, receives her own stem cells via intravenous infusion

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Jun 7, 2024

VetStem Cell Therapy for Exotic Animals

Posted by Bob under Exotic Animals

As June is National Zoo and Aquarium Month, we thought it fitting to discuss the work VetStem has done with exotic animal organizations across the United States. As most of you know, VetStem Cell Therapy is primarily used in dogs and horses to treat orthopedic conditions. We also do a lot of work with cats to treat alternative conditions such as chronic kidney disease and gingivostomatitis. But did you know VetStem Cell Therapy has also helped to improve the lives of several exotic species?

VetStem has worked with numerous zoos, aquariums, and exotic animal refuges to provide stem cell therapy for multiple species. One of our biggest exotic programs has been with elephants who are infected with a virus known as Elephant Endotheliotropic Herpesvirus (EEHV). EEHV is a lethal viral infection that can cause a highly fatal hemorrhagic disease. Stem cells have numerous mechanisms of action, including the secretion of molecules that are anti-viral. VetStem has provided stem cell doses to several zoos in the United States who had elephants with EEHV and has gathered some promising data. While there is still research to be done, we are optimistic that stem cell therapy may be a viable treatment option for elephants with EEHV.

We have also seen success using stem cells in a couple of bears. Francis is a sun bear from the San Diego Zoo that received VetStem Cell Therapy for arthritis in several joints. According to his keepers, Francis’ symptoms improved and he was climbing more after receiving stem cell therapy. Brody, a black bear in Florida, was a juvenile when he received VetStem Cell Therapy in conjunction with surgery for a condition that is similar to hip dysplasia in dogs. Dr. Jeff Christiansen, a board-certified veterinary surgeon and longtime VetStem proponent, performed his surgery and stem cell therapy. Check out a video of Brody from the Brevard Zoo to get more details about his story: https://www.youtube.com/watch?v=MGu4siQNNnU

VetStem has also been used in numerous aquatic species. We have provided cell therapy services for dolphins, whales, penguins, sea lions, sea turtles, and more. Aquatic animals have received stem cells for various conditions including arthritis, corneal conditions, and acute injuries such as this sea turtle who was injured by a propeller.

These are just a few examples of the many exotic species that have received VetStem Cell Therapy. We have provided stem cell services for over 60 species! As leaders in the field of regenerative veterinary medicine, we take our job very seriously when it comes to the research and development of innovative regenerative medicine treatments for animals and diseases that have minimal treatment options. Maintaining the health and well-being of endangered exotic animals is particularly crucial and has become a community effort, bringing together veterinarians, scientists, and those in the animal health field across the globe. We are happy to contribute to the mission and will continue our own research to develop potentially life-saving stem cell treatments for these animals.

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Oct 27, 2023

VetStem Cell Therapy for Cats: Three Common Uses

National Cat Day is fast approaching, and we never miss an opportunity to talk about VetStem Cell Therapy for cats. While stem cells are primarily used for orthopedic conditions, many veterinarians have used VetStem Cell Therapy to help treat and control symptoms associated with diseases such as kidney disease, gingivostomatitis, and inflammatory bowel disease.
All three of these diseases are prevalent in cats and have limited treatment options.

Stem Cells for Kidney Disease

Kidney disease is one of the most common causes of sickness and death in cats. Common symptoms can include weight loss, lethargy, variable appetite, and poor coat quality. Some cats may also drink and urinate more, vomit, or have diarrhea.Unfortunately, treatment options for cats with kidney disease are limited and can be costly.

The good news is, based upon our own data as well as the data of others, we believe that stem cells may help improve the symptoms and quality of life in some cats with kidney disease. In fact, a review of a small number of feline patients treated with VetStem Cell Therapy showed that blood kidney values were slightly to moderately improved after treatment. Owners and veterinarians have also reported improved appetites, weight gain, and increased energy in cats treated with VetStem Cell Therapy.

Stem Cells for Gingivostomatitis

Gingivostomatitis is another debilitating condition found in cats. It is characterized by chronic inflammation of the gums, which can lead to inappetence, reduce grooming, and weight loss. Unfortunately, there is no cure for this disease. Common treatments include lifelong medical management with antibiotics, steroids, and pain medications and/or full mouth teeth extractions.

A recent clinical study demonstrated that intravenous administration of adipose (fat) derived stem cells could ameliorate the clinical signs of gingivostomatitis. Additionally, veterinarians and cat owners have reported an improvement in symptoms and quality of life in cats treated with VetStem Cell Therapy.

Stem Cells for Inflammatory Bowel Disease

Inflammatory Bowel Disease (IBD) is an intestinal disorder that affects both cats and dogs. It is characterized by inflammation of the intestines and can cause vomiting, diarrhea, reduced appetite, and weight loss. It is important to note however, that these symptoms can be indicative of several conditions including feline lymphoma. Since VetStem Cell Therapy is contraindicated in pets with cancer, it is essential to rule this out before pursuing treatment with stem cells.

Multiple cats have received VetStem Cell Therapy for IBD (dogs too!). And we have had reports from veterinarians and owners regarding the improvement of their patients and pets after treatment with stem cells. Additionally, in a recently published paper, 5 out of 7 IBD cats that were treated with stem cells significantly improved or had complete resolution of symptoms, whereas the 4 control cats had no improvement.

If you think your cat may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

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Oct 20, 2023

VetStem had a busy week attending veterinary conferences!

Posted by Bob under Veterinary Medicine, VetStem

We spent the better part of last week attending two different veterinary conferences. We love attending these shows as they are a great way to meet with existing and potential clients to talk all things regenerative veterinary medicine. They allow us the opportunity to speak to and educate veterinarians and veterinary technicians from all over the country about VetStem Cell Therapy and how they can implement this therapeutic modality in their practice.

The first part of the week was spent in Atlantic City for the Fetch Coastal veterinary conference. This is a smaller group consisting primarily of small animal veterinarians. Many showed interest in regenerative medicine and our platelet-rich plasma options. Fetch hosts multiple shows throughout the U.S. We attended Fetch DVM360 in Kansas City in August and will attend Fetch Long Beach later this year.

Over the weekend, the team was in Memphis for the annual American Association of Feline Practitioners conference. AAFP is a great show with tons of enthusiastic cat vets. Many veterinarians at this conference show interest in our clinical research programs, such as inflammatory bowel disease, gingivostomatitis, and renal disease, as these conditions tend to be prevalent in cats and have limited treatment options.

If you missed us at these shows, don’t worry! Show season is not over yet! You can find VetStem at the American Association of Equine Practitioners (AAEP) conference and Fetch Long Beach in late November/Early December. And we will of course be back in Las Vegas in February for the Western Veterinary Conference.

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Mar 31, 2023

VetStem Cell Therapy for Feline Asthma

Posted by Bob under Cat Stem Cells, VetStem Cell Therapy

While VetStem Cell Therapy is primarily used to treat orthopedic conditions, many patients have received stem cell therapy for alternate indications such as kidney disease, gingivostomatitis, and inflammatory bowel disease. Conditions such as these are still in the investigational stage, as there is minimal published data to demonstrate that stem cells are effective in treating these diseases.

That being said, it is well documented that stem cells have anti-inflammatory properties, which, theoretically, may make them effective at treating a wide range of inflammatory diseases and processes. One example of an inflammatory disease is feline asthma.

Asthma is defined as a chronic inflammatory process involving the tracheal, bronchi, and lung fields. Cats with asthma often have a chronic cough, acute respiratory distress, and vomiting. There is currently no cure for feline asthma so traditional treatment is focused on managing the disease with oxygen, inhalers, and steroids. As one can imagine, getting a cat to cooperate with using an inhaler is not always easy. And long-term steroid use comes with several negative side effects.

That’s where VetStem Cell Therapy comes in. Stem cells have the ability to home to areas of inflammation and down-regulate that inflammation. Not only can they control inflammatory processes, stem cells can also modulate the immune system, which may play a role in reducing the number of acute asthmatic episodes in an affected cat. Some cats have received VetStem Cell Therapy for asthma, and while much of the evidence is anecdotal at this point, we have received reports of improvement in symptoms and one case where the cat went into complete remission. That being said, we still have much to learn about using VetStem Cell Therapy to treat feline asthma. And it is important to note that every patient reacts differently to treatment with stem cells.  

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Oct 28, 2022

The Future is Now: VetStem Cell Therapy for Cats

Tomorrow is National Cat Day and what perfect timing since our sales and marketing team is currently at the annual American Association of Feline Practitioners (AAFP) conference! For the past few years, VetStem has been a bronze sponsor at this conference and has delivered a talk on the topic of VetStem Cell Therapy for cats to veterinarians and veterinary technicians.

This year, VetStem’s very own Dr. Anne Hale will be delivering a talk entitled Evidence Based Medicine Supporting Stem Cell Therapy in the Feline Patient. In her talk, Dr. Hale will discuss the potential uses of VetStem Cell Therapy in cats. As many of you know, veterinarians have used stem cells to treat renal disease, both acute and chronic, inflammatory bowel disease, gingivostomatitis, and more in cats. This year, Dr. Hale will also introduce a few feline clinical trials that VetStem will be enrolling for soon.

We find AAFP to be one of our favorite shows. From the attendees to the educational offerings, this show has a lot to offer. Feline medicine is unique in the field of veterinary medicine. For a long time, cats were often treated like small dogs. However, there are several physical and physiological differences between cats and dogs that are important to understand from a caregiving standpoint.

One major difference is that cats metabolize drugs very differently than dogs. This is why there are limited treatment options when it comes to pain in cats. While dogs tend to tolerate NSAIDs and other pain medications relatively well, cats do not. There are some NSAIDs approved for short-term post-operative use in cats, but there are currently no veterinary NSAIDs approved for safe, long-term use to control osteoarthritis pain in cats.

This is one of the reasons that technologies such as VetStem Cell Therapy are so important in feline medicine. Stem cells can help control pain and inflammation, can regulate the immune system, and can help regenerate damaged tissues. This makes stem cell therapy a potential treatment option for a wide array of diseases that are lacking effective treatment protocols in cats.

If you think your cat may benefit from VetStem Cell Therapy, speak to your veterinarian or contact us to find a VetStem provider near you.

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