Tomorrow is National French Bulldog Day! These snuggly, squished-face cuties have gained popularity in recent years but, as is the case with many purebred dogs, it’s important to note that they are susceptible to certain health conditions including spinal disorders. One of the most common neurological conditions affecting Frenchies is Intervertebral Disc Disease (IVDD).

IVDD is a degenerative condition that affects the spinal discs in dogs. In French Bulldogs, IVDD can be particularly problematic due to their unique body structure. With their short legs and long bodies, extra strain is placed on their intervertebral discs. When the discs become weakened or herniated, this causes compression on the surrounding nerves and/or spinal cord, which can lead to pain and mobility issues, including temporary or permanent paralysis.

One example is Lady Josephine Beatrix Von Snugglebottom (aka Jojo). At just 6 months old, she was suffering from severe IVDD and spinal cord compression. At the time, she was unable to use her back legs for about one month. Jojo underwent surgery to relieve the pressure on her spine and aid in preventing further damage. She also received daily laser therapy and weekly acupuncture treatments. There was noticeable improvement in the strength in her legs, and she was able to hold herself up unassisted approximately two months after surgery. She still required a wheelchair however.

Shortly thereafter, Jojo was treated with VetStem Cell Therapy to aid the further healing of her spine. She received two intravenous injections of her own stem cells approximately one month apart. Her owner noted that following the treatment with stem cells, she was finally able to get around without her wheelchair. She began to run and, according to her owner, she hasn’t stopped since! Check out this adorable video of Jojo.

While many veterinarians have treated similar conditions with VetStem Cell Therapy and have seen remarkable results, it’s important to note that the research is ongoing for this condition and each dog will respond differently to treatment. A case such as Jojo’s falls under our Clinical Research Program for canine back pain. If you think your pet may benefit from treatment with VetStem Cell Therapy, speak to your veterinarian or contact us to receive a list of VetStem providers near you.

We frequently share stories about dogs that received VetStem Cell Therapy for orthopedic conditions such as osteoarthritis and injured cruciate ligaments. But stem cell therapy may potentially help a number of other conditions. Veterinarians have used VetStem Cell Therapy to treat various diseases including renal failure, inflammatory bowel disease, gingivostomatitis, and dry eye.

VetStem Clinical Research Programs

All of the above diseases fall under our Clinical Research Programs. These programs are designed to evaluate the safety and possible effectiveness of stem cell therapy for specific conditions before we move on to performing a clinical trial. Another current Clinical Research Program is for Canine Back Pain. This is obviously a broad condition so feel free to read our blog about this particular program. One condition that falls under the Canine Back Pain program is Intervertebral Disc Disease.

Intervertebral Disc Disease

Intervertebral Disc Disease (IVDD) is a condition in which one or several intervertebral discs in the spine bulge, resulting in pressure on the spinal cord. This pressure may result in extreme pain and possibly loss of limb function. IVDD can be a result of chronic disc degeneration or from an acute injury. Conservative treatment with pain medications and anti-inflammatories may help patients who have a gradual onset of symptoms or whose symptoms are mild. In severe cases or when there are repeated episodes, surgery may be recommended.

Bailee Received VetStem Cell Therapy for IVDD

Bailee, an English Springer Spaniel, was approximately fourteen years old when he injured his neck. He jumped off a deck that was about four feet off the ground and yelped in pain. He was diagnosed with IVDD and was prescribed pain medications. Unfortunately, the medications made him very lethargic and did not help his pain so his owner sought a second opinion.    

Dr. Susan Burkhart of Animal Medical Center of Ontario examined Bailee and recommended treatment with VetStem Cell Therapy. Within one week after his stem cell therapy, Bailee’s owner reported that she noticed a huge difference. She stated, “He was once again smiling, and out of pain. It has been 2.5 years since then, and Bailee is one happy pup, once again, and able to live many more years pain free. I am so grateful and would do again for any of my pets.”

While stem cells have demonstrated the ability to reduce pain and inflammation, there is limited data to support the use of stem cell therapy for the treatment of IVDD. Since this condition develops for different reasons, the stem cell protocol and outcome can vary for each dog. Any inquiries regarding treatment of similar conditions or other non-standard indications should be directed to VetStem personnel.

VetStem had the privilege of exhibiting at the 2025 Western Veterinary Conference (WVC) this week, one of the largest and most anticipated events in veterinary medicine. As leaders in regenerative medicine, VetStem showcased its innovative stem cell therapy and off-the-shelf PRP products, which are revolutionizing how veterinarians treat a number of diseases and injuries.

This year, we were excited to announce the news that we entered into an Exclusive License and Supply Agreement with Petvivo Animal Health, Inc. to commercialize our innovative allogeneic orthobiologic products, PrecisePRP™ Canine and PrecisePRP™ Equine. PrecisePRP™ is a groundbreaking, off-the-shelf platelet-rich plasma (PRP) product designed for ease of use by veterinarians. Unlike traditional PRP mechanical kits that require a blood draw and centrifugation, PrecisePRP™ is ready-to-use, offering veterinarians a truly off-the-shelf product that is easy and convenient. More importantly, PrecisePRP™ ensures uniformity and consistency with its unique patent-pending manufacturing process and quality testing.

Additionally, attendees had the opportunity to learn about VetStem’s groundbreaking advancements in stem cell technology, which are helping thousands of pets recover from injuries, arthritis, and other challenging conditions like renal disease, inflammatory bowel disease, gingivostomatitis, back pain/IVDD, and dry eye.

We were thrilled to connect with veterinarians and industry professionals at the event. It was a great opportunity to share how VetStem’s regenerative solutions are improving the health and quality of life for animals everywhere. Thank you to everyone who stopped by and made our time at WVC 2025 such a success. We look forward to continuing to drive advancements in veterinary care and supporting the veterinary community in the years to come!

August 26^th is National Dog Day. This day was founded in 2004 and celebrates dogs of all breeds. The stated mission is to bring attention to all the dogs that need rescuing as well as honor both family dogs and working dogs. For our own celebration, we would like to discuss the various uses of VetStem Cell Therapy in dogs!

VetStem Cell Therapy for Dogs

Though the first patient to be treated with VetStem Cell Therapy was a horse, dogs followed closely behind. Initially, we worked with select veterinary clinics to evaluate the use of VetStem Cell Therapy for osteoarthritis (OA) and orthopedic soft tissue injures such as cruciate ligament tears. After several years of collecting and analyzing data, we published two peer-reviewed studies. The first, in 2007, evaluated the use of stem cells for chronic hip OA. The second was published in 2008 and looked at stem cells for chronic elbow OA. Both studies concluded that treatment with VetStem Cell Therapy led to reduced lameness and pain as well as increased range of motion in the affected dogs.

VetStem Cell Therapy for More than OA

Though dogs were initially treated primarily for orthopedic conditions, we eventually broadened our research interests. Veterinarians have now used VetStem Cell Therapy to treat a wide array of conditions in dogs including organ failure, inflammatory bowel disease, back pain, and keratoconjunctivitis sicca (KCS or “Dry Eye”). Though we do not have any completed peer-review studies for these conditions, some dogs have experienced good results!

VetStem Cell Therapy for Canine Back Pain and IVDD

Canine back pain is one of VetStem’s current clinical research programs. A clinical research program is designed to evaluate the safety and possible effectiveness of VetStem Cell Therapy for specific conditions. One condition that falls under our back pain clinical research program is intervertebral disc disease (IVDD). This is a condition in which one or several intervertebral discs in the spine bulge, resulting in pressure on the spinal cord and leading to pain and possibly the loss of limb function. While IVDD can potentially be a devastating disease, several owners have reported improvement in their dog after treatment with VetStem Cell Therapy including Bella and Bailee.

If you think your dog may benefit from VetStem Cell Therapy, even if he/she is not suffering form an orthopedic condition, we recommend speaking to your veterinarian or contacting us to find VetStem providers near you.

In this week’s blog, we are sharing Bella’s story. Bella, a pit bull, was approximately twelve years old when she received VetStem Cell Therapy. She was previously diagnosed with Intervertebral Disc Disease (IVDD) and pain medication, unfortunately, brought her little relief.

Intervertebral Disc Disease

IVDD is a condition in which one or several intervertebral discs in the spine bulge, resulting in pressure on the spinal cord. This pressure may result in extreme pain and possibly loss of limb function. IVDD can be a result of chronic disc degeneration or from an acute injury. Conservative treatment with pain medications and anti-inflammatories may help patients who have a gradual onset of symptoms or whose symptoms are mild. In severe cases or when there are repeated episodes, surgery may be recommended.

Bella’s mom, a veterinary technician at Fort Lee Animal Clinic, noticed that Bella stopped jumping on and off furniture and was restless and unable to sleep comfortably at night. After researching her options, she decided to have Bella treated with her own stem cells. Dr. Nazar Pereymybida at Fort Lee Animal Clinic agreed that Bella may benefit from stem cell therapy and Bella became his first stem cell case.

Treatment with VetStem Cell Therapy

To begin the process, Dr. Pereymybida collected fat tissue from Bella’s abdomen in a minimally invasive anesthetic procedure. The fat was aseptically packaged and shipped to the VetStem laboratory in Poway, California. Once received, VetStem lab technicians processed the fat to extract and concentrate Bella’s stem and regenerative cells. Stem cell injections were prepared and shipped back to Dr. Pereymybida. Approximately 48 hours after the initial fat collection procedure, Bella received multiple injections of her own stem cells along her paraspinal muscles as well as intravenously.

Stem cell treatment of IVDD falls under VetStem’s clinical research program for canine back pain. This program is designed to evaluate the safety and potential effectiveness of stem cells for numerous canine back conditions.

Results

Approximately two months after receiving VetStem Cell Therapy, Bella’s owner reported that her symptoms had improved! Though Bella was still on pain medications, her owner stated, “She’s now jumping on and off the bed and seems less painful and more energetic.” In addition, Bella was able to sleep comfortably through the entire night.

Unfortunately, Bella was diagnosed with cancer earlier this year. Her condition progressed rapidly and she crossed over the rainbow bridge.

While there is still more to learn about using VetStem Cell Therapy to treat canine IVDD, Bella’s case is not the only positive outcome reported. You may remember Bailee’s story from a while ago. He also received VetStem Cell Therapy for IVDD after an injury to his neck. And like Bella, Bailee also experienced a reduction in pain after treatment.

If your dog has IVDD or another painful back condition, speak to your veterinarian about the possibility of treatment with VetStem Cell Therapy. Since these conditions develop for different reasons, the stem cell protocol and outcome can vary for each dog. Any inquiries regarding treatment of similar conditions or other non-standard indications should be directed to VetStem personnel.